Now showing items 11-20 of 128
Neurabin-I is phosphorylated by Cdk5 : Implications for neuronal morphogenesis and cortical migration
The correct morphology and migration of neurons, which is essential for the normal development of the nervous system, is enabled by the regulation of their cytoskeletal elements. We reveal that Neurabin-I, a neuronal-specific ...
Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons
There is growing interest in the potential beneficial effects of flavonoids in the aging and diseased brain. We have investigated the potential of the flavanone hesperetin and two of its metabolites, hesperetin-7-O-beta- ...
Purinergic 2X receptors mediate endothelial dependent vasodilation to ATP
ATP is an important endogenous mediator in the cardiovascular system. It induces endothelium dependent vasodilation, but the precise receptor pathway activated in this response is currently under debate. We have used ...
Proteomic biomarkers of peripheral blood mononuclear cells obtained from postmenopausal women undergoing an intervention with soy isoflavones
The incidence of cardiovascular diseases increases after menopause, and soy consumption is suggested to inhibit disease development.
Anger, disgust, and presumption of harm as reactions to taboo-breaking behaviors
Three experiments investigated the relationship between the presumption of harm in harmfree violations of creatural norms (taboos) and the moral emotions of anger and disgust. In Experiment 1, participants made a presumption ...
Defense against Sclerotinia sclerotiorum in Arabidopsis is dependent on jasmonic acid, salicylic acid, and ethylene signaling
Genotypic differences in susceptibility of Arabidopsis thaliana to Sclerotinia sclerotiorum have not been reported due to the extreme susceptibility of this cruciferous plant. To overcome this limitation, we have established ...
White is a colour too : Engaging actively with the risks, challenges and rewards of cross-cultural family therapy training and practice
Due to increased global mobility and displacement there is a growing cultural diversity within therapeutic encounters between therapists and clients. Literature on cross-cultural therapy traditionally focuses on the culture ...
Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols
The death of nigral neurons in Parkinson's disease is thought to involve the formation of the endogenous neurotoxin, 5-S-cysteinyl-dopamine. In the present study, we show that the polyphenols, (+)-catechin and caffeic acid, ...
Effects of pathogen polygalacturonase, ethylene, and firmness on interactions between pear fruits and Botrytis cinerea
The plant hormone ethylene regulates developmental processes as well as responses to abiotic stress and pathogens. Ethylene influences interactions between the gray mold pathogen, Botrytis cinerea, and its hosts. The primary ...
The Agricultural Document Library (ADLib) and its applications
In April 2004 the Agricultural Document Library (ADLib) was launched (www.adlib.ac.uk). It has been developed jointly by the Agriculture and Environment Research Unit (AERU) at the University of Hertfordshire and TLR ...