Now showing items 21-30 of 32
Bioprosthetic valve thrombosis and degeneration following transcatheter aortic valve implantation (TAVI)
Bioprosthetic valve thrombosis (BPVT) is a recognised complication of prosthetic aortic valves and can be seen in up to 13% of patients after transcatheter implantation.The mechanism of BPVT is not well known, abnormal ...
Reduction in ACE2 may mediate the prothrombotic phenotype in COVID-19
This commentary refers to ‘Characteristics and outcomes of patients hospitalized for COVID-19 and cardiac disease in Northern Italy’, by R.M. Inciardi et al., doi: 10.1093/eurheartj/ehaa583.
Antithrombotic therapy in patients with atrial fibrillation and acute coronary syndrome
Abstract: Acute coronary syndrome and atrial fibrillation are both common, and can occur in the same patient. Combination therapy with dual antiplatelet therapy and oral anticoagulation increases risk of bleeding. Where ...
Point-of-care Platelet Function Tests: Relevance to Arterial Thrombosis and Opportunities for Improvement
Studies using whole blood platelet aggregometry as a laboratory research tool, provided important insights into the mecha- nism and modulators of platelet aggregation. Subsequently, a number of point-of-care (POC) platelet ...
Angiotensin Converting Enzyme 2 may mediate disease severity in COVID-19
Identification of vulnerability to severe coronavirus disease 2019 (COVID-19) is extremely important and might allow optimised shielding and easing of lockdown. The disease is attributed to the severe acute respiratory ...
Usefulness of the NULL-PLEASE Score to predict 1 survival in out-of hospital cardiac arrest
Purpose: Out-of-hospital cardiac arrest (OHCA) carries a very high mortality even after successful cardiopulmonary resuscitation. Currently, information given to relatives regarding prognosis following resuscitation is ...
MINOCA presenting with STEMI- a review of incidence, aetiology, assessment and treatment
Myocardial infarction with non-obstructive coronary artery (MINOCA) is a condition previously thought to be benign but has recently been shown to have comparable mortality to that of acute coronary syndrome with obstructive ...
Effect of remote ischaemic conditioning on platelet reactivity and endogenous fibrinolysis in ST-elevation myocardial infarction- a substudy of the CONDI-2/ERIC4 PPCI randomised controlled trial
Background: Remote ischaemic conditioning (RIC) has been shown to reduce myocardial infarct size in animal models of myocardial infarction. Platelet thrombus formation is a critical determinant of outcome in ST-segment ...
Antithrombotic therapy in patients with acute coronary syndrome complicated by cardiogenic shock or out-of-hospital cardiac arrest: a Joint Position Paper from the European Society of Cardiology (ESC) Working Group on Thrombosis, in association with the Acute Cardiovascular Care Association (ACCA) and European Association of Percutaneous Cardiovascular Interventions (EAPCI)