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The effect of podophyllotoxin on microtubule dynamics
(1989)
We have investigated the effects of podophyllotoxin on the dynamic properties of microtubules assembled from pure tubulin dimer. Excess podophyllotoxin causes the complete disassembly of microtubules, through formation of ...
Flunixin pharmacokinetics and serum thromboxane inhibition in the dog
(1989)
Flunixin meglumine administered orally to beagle dogs at doses of 0.55, 1.10 or 1.65 mg/kg bodyweight was rapidly absorbed to produce maximum mean plasma concentrations of 2.40 +/- 0.70, 4.57 +/- 1.12 and 7.42 +/- 2.07 ...
Current models in pharmacokinetics : applications in veterinary pharmacology
(1989)
Major advances in developing models for pharmacokinetic studies have been made in recent years, and different approaches can now be employed. These include the use of (1) compartmental models, (2) non-compartmental models, ...
Relay bioavailability and toxicity of isometamidium residues : a model for human risk assessment
(1989)
The bioavailability and potential toxicity of the residues of the antitrypanosomal drug isometamidium (ISMM) in bovine tissues were investigated in male Sprague-Dawley rats. They were allowed to feed for 7 and 21 days on ...
Automatic and strategic volitional saccadic eye movements in psychotic patients
(1989)
Drug-free schizophrenics were compared with depressive psychotics and normal controls on two saccade initiation tasks which differed with respect to the type of stimulus that initiated a saccadic response. Strategic ...
Effect of an antimuscarinic drug on the plasma pepsinogen activity of sheep infected with Ostertagia circumcincta
(1989)
The antimuscarinic drug atropine caused a marked fall in plasma pepsinogen values of sheep with burdens of Ostertagia circumcincta and this response was greater in animals which had higher plasma pepsinogen values before ...
Teacher behaviour: a determinant of student self esteem
(1989)
This small scale piece of research was undertaken to establish whether there existed a relationship between teacher behaviour and the reported self esteem inventories of four students. Using a low inference category system ...
New Zealand - changing patterns of international tourism
(1989-01-01)
The number of overseas tourists to New Zealand continues to increase although the 15.6% annual growth rate of the 1960s is no longer achievable, having fallen to 7.55% in the 1980s. Dr Stephen Page of the Department of ...