Now showing items 21-30 of 70
Food supply chain governance and public health externalities : upstream policy interventions and the UK state
Contemporary food supply chains are generating externalities with high economic and social costs, notably in public health terms through the rise in diet-related non-communicable disease. The UK State is developing policy ...
The phagocytic capacity of neurones
Phagocytosis is defined as the ingestion of particulates over 0.5 microm in diameter and is associated with cells of the immune system such as macrophages or monocytes. Neurones are not generally recognized to be phagocytic. ...
Identification and insertion of 3-carbon bridges in protein disulfide bonds : A computational approach
More than 42,000 3D structures of proteins are available on the Internet. We have shown that the chemical insertion of a 3-carbon bridge across the native disulfide bond of a protein or peptide can enable the site-specific ...
Immunomodulatory effects of schistosome cercarial interactions with human keratinocytes and Langerhans cells
The human parasite Schistosoma mansoni is known to modulate host immune responses in order to promote its own survival. However, studies investigating the interaction between the skin-invading cercarial stage and cells of ...
Champagne wine polyphenols protect primary cortical neurons against peroxynitrite-induced injury
White wines are generally low in polyphenol content as compared to red wines. However, Champagne wines have been shown to contain relatively high amounts of phenolic acids that may exert protective cellular actions in vivo. ...
Variability in human skin permeability in vitro: Comparing penetrants with different physicochemical properties
Appreciating and compensating for the inherent variability associated with percutaneous absorption is essential in optimizing (trans)dermal therapy. In this study, the variability in human skin permeability associated with ...
The SECURE project – Stem canker of oilseed rape: : molecular methods and mathematical modelling to deploy durable resistance
Modelling done during the SECURE project has demonstrated the dynamic nature of the interaction between phoma stem canker (Leptosphaeria maculans), the oilseed rape host (Brassica napus) and the environment. Experiments ...
Disruption of methylarginine metabolism impairs vascular homeostasis
Asymmetric dimethylarginine (ADMA) and monomethyl arginine (L-NMMA) are endogenously produced amino acids that inhibit all three isoforms of nitric oxide synthase (NOS)(1). ADMA accumulates in various disease states, ...
(John Wiley & Sons, 2007)
Use of fungicide sprays to control stem canker (Leptosphaeria maculans) in winter oilseed rape
(Association of Applied Biologists, 2007)