Now showing items 21-30 of 383
Overcoming the nail barrier : A systematic investigation of ungual chemical penetration enhancement
This study investigated the in vitro nail permeability of penetrants of varying lipophilicity—caffeine (CF, log P −0.07), methylparaben (MP, log P 1.96) and terbinafine (TBF, log P 3.3) and the effect of 2 novel penetration ...
Bidirectional transport of amino acids regulates mTOR and autophagy
Amino acids are required for activation of the mammalian target of rapamycin (mTOR) kinase which regulates protein translation, cell growth, and autophagy. Cell surface transporters that allow amino acids to enter the cell ...
Mutation in acetylcholinesterase1 associated with triazophos resistance in rice stem borer, Chilo suppressalis (Lepidoptera: Pyralidae)
Two full-length genes encoding different acetylcholinesterases (AChEs), designated as Ch-ace1 and Ch-ace2 were cloned from strains of the rice stern borer (Chilo suppressalis) susceptible and resistant to the organophosphate ...
Basic molecular biology techniques
(The Royal Society of Chemistry, 2009)
Hydrology of the combination irrigation system in the Wadi Faynan, Jordan
The field system of the Wadi Faynan in southern Jordan was fed by an ancient combination irrigation system that incorporated runoff farming and diversion irrigation techniques. The hydraulic characteristics of this system ...
Associations of Physical Activity With Inflammatory Factors, Adipocytokines, and Metabolic Syndrome in Middle-Aged and Older Chinese People
Inflammatory factors, adipocytokines, and the metabolic syndrome are important determinants of cardiometabolic disease. It remains unclear how physical activity is related to these risk factors. Our objective was to ...
A novel concept in enteric coating : a double-coating system providing rapid drug release in the proximal small intestine
A novel double-coating enteric system was developed to accelerate drug release in conditions resembling the upper small intestine. The system comprises an inner coat (partially neutralised EUDRAGIT® L 30 D-55 and organic ...
Controlling crop disease contributes to both food security and climate change mitigation
Global food security is threatened by crop diseases that account for average yield losses of 16 per cent, with the greatest losses experienced by subsistence farmers in the developing world. Climate change is exacerbating ...