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Now showing items 31-39 of 39
Point-of-care Platelet Function Tests: Relevance to Arterial Thrombosis and Opportunities for Improvement
(2020-06-11)
Studies using whole blood platelet aggregometry as a laboratory research tool, provided important insights into the mecha- nism and modulators of platelet aggregation. Subsequently, a number of point-of-care (POC) platelet ...
Angiotensin Converting Enzyme 2 may mediate disease severity in COVID-19
(2020-06-09)
Identification of vulnerability to severe coronavirus disease 2019 (COVID-19) is extremely important and might allow optimised shielding and easing of lockdown. The disease is attributed to the severe acute respiratory ...
Usefulness of the NULL-PLEASE Score to predict 1 survival in out-of hospital cardiac arrest
(2020-05-07)
Purpose: Out-of-hospital cardiac arrest (OHCA) carries a very high mortality even after successful cardiopulmonary resuscitation. Currently, information given to relatives regarding prognosis following resuscitation is ...
MINOCA presenting with STEMI- a review of incidence, aetiology, assessment and treatment
(2020-04-30)
Myocardial infarction with non-obstructive coronary artery (MINOCA) is a condition previously thought to be benign but has recently been shown to have comparable mortality to that of acute coronary syndrome with obstructive ...
Effect of remote ischaemic conditioning on platelet reactivity and endogenous fibrinolysis in ST-elevation myocardial infarction- a substudy of the CONDI-2/ERIC4 PPCI randomised controlled trial
(2020-03-12)
Background: Remote ischaemic conditioning (RIC) has been shown to reduce myocardial infarct size in animal models of myocardial infarction. Platelet thrombus formation is a critical determinant of outcome in ST-segment ...
Impact of Preadmission Morphine on Reinfarction in Patients With ST-Elevation Myocardial Infarction Treated With Percutaneous Coronary Intervention : A Meta-Analysis
(2020-01-28)
Opiates are the traditional analgesics used in patients with ST-elevation myocardial infarction (STEMI). Pharmacodynamic studies indicate that opiates delay the absorption of orally administered P2Y 12 inhibitors and the ...
Platelet inhibition in acute coronary syndrome and PCI: Insights from the past and present
(2020-01-19)
Platelet activation and aggregation have a pivotal role in arterial thrombosis and in the pathogenesis of both acute coronary syndromes (ACS) and in the thrombotic complications that occur in patients undergoing percutaneous ...