Now showing items 31-40 of 56
PEGylation of native disulfide bonds in proteins
PEGylation has turned proteins into important new biopharmaceuticals. The fundamental problems with the existing approaches to PEGylation are inefficient conjugation and the formation of heterogeneous mixtures. This is ...
Prediction of the date of onset of phoma leaf spot epidemics on oilseed rape in the UK
To reduce reliance on fungicides for control of oilseed rape diseases, Decision Support Systems (DSS) are being developed to target applications as part of an integrated disease management strategy. This paper reports on ...
Site-specific PEGylation of native disulfide bonds in therapeutic proteins
Native disulfide bonds in therapeutic proteins are crucial for tertiary structure and biological activity and are therefore considered unsuitable for chemical modification. We show that native disulfides in human interferon ...
A content analysis of involuntary autobiographical memories : examining the positivity effect in old age
Although research on autobiographical memory is growing steadily, very little is known about involuntary autobiographical memories that are spontaneously recalled in everyday life. In addition, very few studies have examined ...