Now showing items 31-40 of 224
Foreword: Special issue—geriatric drug therapy
Age-mediated changes in the gastrointestinal tract
Physiological functions of the two extreme ends of the age spectrum, children (<18 y old) and older adults (aged 65 y and over), differ from healthy young adults. This consequently affects the pharmacokinetic profiles of ...
Acceptability of oral solid medicines in older adults with and without dysphagia : a nested pilot validation questionnaire based observational study
Older patients (aged 65 years and over) are the major consumers of medicines and many barriers affect their ability in taking medicines orally, especially swallowing difficulties. Moreover, the characteristics of differing ...
Genetic variation in target-site resistance to pyrethroids and pirimicarb in Tunisian populations of the peach-potato aphid, Myzus persicae (sulzer) (Hemiptera: Aphididae)
BACKGROUND We used molecular assays to diagnose resistance to pyrethroids and pirimicarb in samples of Myzus persicae from field crops or an insect suction trap in Tunisia. Genotypes for resistance loci were related to ...
Optimization of protein loaded PLGA nanoparticles manufacturing parameters following a quality-by-design approach
Development of a multivariate-based regression model for estimating the critical attributes for establishing a design-space for poly(lactic-co-glycolic acid) (PLGA) nanoparticles formulated by a double emulsion-solvent ...
Digital Learners in Higher Education: Exploring Technology Ownership Patterns and Learning Engagement
(ACPI (Academic Conference Publishing International), 2016-10-26)
Recent studies into ‘digital learners’ have pointed to the high level of digital skills which many UK and US based students entering HE are now demonstrating (White & Beetham, 2013; Pew, 2013). However while students may ...
In vitro recording of mesenteric afferent nerve activity in jejunal and colonic segments from rodents
Afferent nerves not only convey information concerning normal physiology, but also signal disturbed homeostasis and pathophysiological processes of the different organ systems from the periphery towards the central nervous ...
Is Endotoxemia in Stable Hemodialysis Patients an Artefact? : Limitations of the Limulus Amebocyte Lysate Assay and Role of (1→3)-β-D Glucan
BACKGROUND: Elevated blood endotoxin levels are frequently reported in the dialysis population and are strongly linked with inflammation, a major predictor of mortality. Virtually all studies have employed the Limulus ...
Risk-adjusted survival for adults following in-hospital cardiac arrest by day of week and time of day: observational cohort study
Background Internationally, hospital survival is lower for patients admitted at weekends and at night. Data from the UK National Cardiac Arrest Audit (NCAA) indicate that crude hospital survival was worse after in-hospital ...
Squeezy Green Balls: Promoting Environmental Awareness through Playful Interactions
(ACM Digital Library, 2016-10-16)
We need collective action to tackle global warming. However, research shows that people switch off from being concerned about the environment because they are often too busy, or fail to appreciate their ability to make a ...