Search
Now showing items 71-80 of 81
Cancer cell expulsion of anticancer drugs through shedding of microvesicles: association with drug resistance and tumour survival
(2012-09-13)
Microvesicles (MVs) are small (0.1-≤1 µm in diameter) heterogeneous vesicles released from cells constitutively or upon activation, that mediate intercellular communication. Multi-drug resistance (MDR) has been defined as ...
Decoding actions and emotions in deaf children: Evidence from a biological motion task
(2012-07-31)
This study aimed to explore the recognition of emotional and non-emotional biological movements in children with severe and profound deafness. Twenty-four deaf children, together with 24 control children matched on mental ...
Coloured filters enhance the visual perception of social cues in children with autism spectrum disorders
(2012)
Coloured filters have been found to reduce visual distortion of text in children with autism spectrum disorders (ASD). We investigated the effect of the overlays on the "mind in the eye" task in children with ASD and ...
Home haemodialysis : trends in technology
(2011-12-01)
Self management and home-based dialysis therapies offer the prospect of improved patient experience and outcomes. To allow more patients to realize these benefits requires changes in technology which focus on maximizing ...
Response to commentaries
(2011-12-01)
Dr Klein‟s assertions about the origins of registers on drug-related death are inaccurate, probably due to misunderstanding some of the fundamental epidemiological indicators of drug misuse, including mortality. Whilst it ...
Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses
(2011-06-01)
The crystal structure of the TLR4-MD-2-LPS complex responsible for triggering powerful pro-inflammatory cytokine responses has recently become available. Central to cell surface complex formation is binding of lipopolysaccharide ...
Alternative HER/PTEN/Akt pathway activation in HPV positive and negative penile carcinomas
(2011-03-10)
Background: The pathogenesis of penile squamous cell carcinoma (PSCC) is not well understood, though risk factors include human papillomavirus (HPV). Disruption of HER/PTEN/Akt pathway is present in many cancers; however ...
Women’s spending behaviour is menstrual-cycle sensitive
(2011)
When considering why women are more prone to money pathologies than men the influence of ovarian hormones cannot be ruled out. The phases of the menstrual-cycle are known to have a range of behavioural, psychological and ...
Pathogenesis, parasitism and mutualism in the trophic space of microbe-plant interactions
(2010-08)
Microbe host interactions can be categorised as pathogenic, parasitic or mutualistic, but in practice few examples exactly fit these descriptions. New molecular methods are providing insights into the dynamics of microbe ...
Effect of a novel penetration enhancer on the ungual permeation of two antifungal agents
(2010-06)
Objectives The aim of this study was to demonstrate the effect of a novel permeation enhancer system using two existing marketed nail lacquers and the delivery of terbinafine through human nail samples in vitro. Methods ...