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Dopaminergic drug treatment remediates exaggerated cingulate prediction error responses in obsessive-compulsive disorder
(2019-08-01)
Rationale: Patients with obsessive-compulsive disorder (OCD) have been found to show exaggerated error responses and prediction error learning signals in a variety of EEG and fMRI tasks, with data converging on the anterior ...
Hyperconnectivity of the ventromedial prefrontal cortex in obsessive-compulsive disorder
(2018-11-30)
Neuroimaging research has highlighted maladaptive thalamo-cortico-striatal interactions in obsessive-compulsive disorder as well as a more general deficit in prefrontal functioning linked with compromised executive ...
Hypoactivation and Dysconnectivity of a Frontostriatal Circuit During Goal-Directed Planning as an Endophenotype for Obsessive-Compulsive Disorder
(2017-11-01)
Background The symptoms of obsessive-compulsive disorder (OCD) have been postulated to result from impaired executive functioning and excessive habit formation at the expense of goal-directed control and have been objectively ...