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Percutaneous coronary intervention with drug-eluting stent versus coronary artery bypass grafting : A meta-analysis of patients with left main coronary artery disease
BACKGROUND: The relative efficacy and safety of percutaneous coronary intervention (PCI) with drug-eluting stents (DES), in comparison to coronary artery bypass grafting (CABG) for left main coronary artery disease (LMCAD) ...
Depression Symptoms in Haemodialysis Patients Predict All-Cause Mortality but Not Kidney Transplantation : A Cause-Specific Outcome Analysis
Background: Depression is common in haemodialysis (HD) patients and associated with poor outcomes. Purpose: To evaluate whether depression symptoms predict survival and transplantation in a large sample of haemodialysis ...
Feasibility study of a randomised controlled trial to investigate the effectiveness of using a humanoid robot to improve the social skills of children with an Autism Spectrum Disorder (Kaspar RCT): A Study Protocol
Introduction: Interventions using robot-assisted therapy may be beneficial for the social skills development of children with autism spectrum disorder (ASD), however randomised controlled trials (RCTs) are lacking. The ...
Trial Protocol for Herts and Minds: Evaluating the effectiveness of Mentalization-Based Treatment (MBT) as an intervention for children in foster care with emotional or behavioural problems: a phase II (feasibility) randomised controlled trial
This document provides details regarding the setting up of, conduct, and analysis of the National Institute for Health Research (NIHR), Research for Patient Benefit (RfPB) funded study, “Evaluating the effectiveness of ...
Impaired thrombolytic status predicts adverse cardiac events in patients undergoing primary percutaneous coronary intervention
Antithrombotic medications reduce thrombosis but increase bleeding. Identification of ST-elevation myocardial infarction (STEMI) patients at risk of recurrent thrombosis could allow targeted treatment with potent antithrombotic ...
Sertraline Versus Placebo in Patients with Major Depressive Disorder Undergoing Hemodialysis : A Randomized, Controlled Feasibility Trial
BACKGROUND AND OBJECTIVES: Depression is common in patients on hemodialysis, but data on the benefits and risks of antidepressants in this setting are limited. We conducted a multicenter, randomized, double-blind, ...