Browsing by Title
Now showing items 12012-12031 of 24095
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Investigation of the protein alkylation sites of the STAT3:STAT3 inhibitor Stattic by mass spectrometry
(2013-08-15)STAT3 (Signal Transducer and Activator of Transcription factor 3) is constitutively active in a wide range of human tumours. Stattic is one of the first non-peptidic small molecules reported to inhibit formation of the ... -
Investigation of the reaction Ge-74(p,gamma)As-75 using the in-beam method to improve reaction network predictions for p nuclei
(2012-09-14)Background: Astrophysical models studying the origin of the neutron-deficient p nuclides require knowledge of proton capture cross sections at low energy. The production site of the p nuclei is still under discussion but ... -
An investigation of the self-propagating high-temperature synthesis of Ti(Si,Al)
(2005-05-01)The self-propagating high-temperature synthesis (SPS) of TiSi and T Si,AL) powders was investigated. Elemental powders of titanium, silicon and aluminum were used for the synthesis. The sample powders were investigated by ... -
Investigation of the stabilisation of freeze-dried lysozyme and the physical properties of the formulations
(2004-07)The long-term stability of a protein formulation requires that the glass transition temperature (T-g) of the formulation should be maximised and the perturbation of the protein native structure in the dried form after ... -
An investigation of the use of Nile Red as a long-wavelength fluorescent-probe for the study of alpha(1)-acid glycoprotein-drug interactions
(1995-07)Spectrofluorimetry in the long-wavelength region of the electromagnetic spectrum (600-1000 nm) is a fairly recent development in photoluminescence spectroscopy, which has numerous advantages over measurements in the more ... -
An investigation of types leading to an examination of some aspects of F-bounded interfaces and the type classes of Haskell
(University of Hertfordshire, 1992)The treatment of types in programming and in type checking is considered briefly and types are distinguished from classes. The subtyping relation is discussed with particular emphasis on the consequences of combining the ... -
An Investigation of Untapered and Tapered Fibre Transmission Properties
(2023-04-14)This thesis is about investigation of untapered and tapered fibre transmission properties by experimentation and simulation. Tapered fibre fabricated from commercial products and custom fibre from Bath University was ... -
Investigation of Varietal Characteristics Required for Sustainable Agriculture : Final report for Defra Project VS0128
(Department for Environment, Food and Rural Affairs (Defra), 2003-07-01) -
Investigation of vehicle ride height and diffuser ramp angle on downforce and efficiency
(2019-07)Diffusers are typically used in motorsport to generate negative lift (downforce). They also reduce aerodynamic drag and so significantly enhance aerodynamic efficiency. The amount of downforce generated is dependent on ... -
Investigation of wear behavior in self-lubricating ABS polymer composites reinforced with glass fiber/ABS and glass fiber/carbon fiber/ABS hybrid
(2023-03-13)A new hybrid fabrication technique was introduced to manufacture composite laminates made of glass fiber, carbon fiber, and acrylonitrile butadiene styrene (ABS) as the matrix. The fabrication process utilized two different ... -
Investigation of α -induced reactions on Sb isotopes relevant to the astrophysical γ process
(2018-04-16)Background: The reaction rates used in γ-process nucleosynthesis network calculations are mostly derived from theoretical, statistical model cross sections. Experimental data is scarce for charged particle reactions at ... -
Investigation on Induced-Residual Stress During End Milling Operation Using Analytical Modelling
(IOS Press, 2018-09-30)During end milling operation, the residual stresses are developed from two sources: plastic deformation of workpiece material and thermal energy generated. These two sources of residual stresses are often combined as one ... -
Investigation on Quantitative Structure-Activity Relationships of 1,3,4 Oxadiazole Derivatives as Potential Telomerase Inhibitors
(2018-07-23)A series of 1,3,4-oxadiazole derivatives with significant broad-spectrum anticancer activity against different cell lines, and demonstrated telomerase inhibition, was subjected to Quantitative Structure-Activity Relationships ... -
Investigation on surface drying and energy savings of the hybrid dryer
(Research Publishing Services, 2010)The feasibility study of a novel heat pump integrated with rotary dehumidifier (desiccant wheel) system for drying process is conducted to obtain the design parameters of the hybrid dryer. The system employed a refrigerant ... -
Investigation on Temperature Control Based on Cooled Mine Compressed Air for Mine Refuge Chamber with High-temperature Surrounding Rock
(2023-05-01)Acceptable temperature is very important for mine refuge chamber (MRC) to ensure the safety of occupants. A novel temperature control scheme combining cold source storage with mine compressed air (MCA) was proposed for ... -
Investigation on the Impact of Protrusion Parameter on the Efficiency of Converting Additional Windage Loss for Ingress Alleviation in Rotor-Stator System
(2016-06-28)This paper presents a detailed investigation on the impact of protrusion parameter including both radial position and amount on the efficiency of cavity with protrusion converting additional windage loss for ingress ... -
An investigation on the morphological evolution of bright-rimmed clouds
(2009)A new radiative driven implosion (RDI) model based on smoothed particle hydrodynamics technique is developed and applied to investigate the morphological evolutions of molecular clouds under the effect of ionizing radiation. ... -
Investigations into Drug Delivery to the Eye: Nanoparticle Comparisons
(University of Hertfordshire, 2014-07-02)Eye disorders are on the rise as a result of an ageing population, an increasing obesity problem and a growth in the number of diabetic patients. Conventional ophthalmic formulations do not maintain therapeutic drug ... -
Investigations into Infrared-Selected Variable Stars
(2024-03-19)The diversity seen in the infrared variable sky is vast, and understudied when compared to variability in the optical regime. Utilising near-infrared (NIR) colours and amplitudes can be a powerful tool in the classification ... -
Investigations into the formulation of metered dose inhalers of salmeterol xinafoate and fluticasone propionate microcrystals
(2008-10)Purpose. To investigate the aerosolization and behaviour of microparticles of salmeterol xinafoate (SX) and fluticasone propionate (FP) suspended in hydrofluoroalkane (HFA) propellant. Methods. Microcrystals of SX and FP ...