Browsing by Title
Now showing items 17028-17047 of 24095
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Polyamine regulation of nitric oxide production in LPS-activated macrophages
(European Communities, 1999)Polyamines are physiological cellular constituents essential for cell growth and differentiation, and regulate a multitude of cellular functions (1-4). Nitric oxide (NO) is an effector molecule in both the cardiovascular ... -
Polyelectrolyte nanoparticles with high drug loading enhance the oral uptake of hydrophobic compounds
(2006-05)In the pharmaceutical industry, orally active compounds are required to have sufficient water solubility to enable dissolution within the gastrointestinal tract prior to absorption. Limited dissolution within the ... -
Polymer architecture dictates thermoreversible gelation in engineered emulsions stabilised with branched copolymer surfactants
(2022-09-26)The generation of materials that switch from a liquid to gel state upon warming can enable new healthcare technologies with improved functionality, such as in situ gel-forming materials for drug delivery to topical or ... -
Polymer Architecture Effects on Poly(N,N‐Diethyl Acrylamide)‐b‐Poly(Ethylene Glycol)‐b‐Poly(N,N‐Diethyl Acrylamide) Thermoreversible Gels and Their Evaluation as a Healthcare Material
(2021-12-11)Thermoreversible gels which transition between liquid‐like and solid‐like states when warmed have enabled significant novel healthcare technologies. Poly(N,N‐diethyl acrylamide) (PDEA) is a thermoresponsive polymer which ... -
Polymerase Chain Reaction
(Humana Press, 1998) -
A polymerase chain reaction (PCR) assay for the detection of inoculum of Sclerotinia sclerotiorum
(2002-11)The development of a polymerase chain reaction (PCR) assay for the detection of inoculum of the plant pathogenic fungus Sclerotinia sclerotiorum is described. The PCR primers were designed using nuclear ribosomal DNA ... -
Polymeric gels for intravaginal drug delivery
(2018-01-28)Intravaginal drug delivery can elicit a local effect, or deliver drugs systemically without hepatic first pass metabolism. There are a number of emerging areas in intravaginal drug delivery, but the vagina is a challenging ... -
Polymeric microcapsules with switchable mechanical properties for self-healing concrete : Synthesis, characterisation and proof of concept
(2017-03-14)Microcapsules, with sodium silicate solution as core, were produced using complex coacervation in a double, oil-in-water-in oil, emulsion system. The shell material was a gelatin-acacia gum crosslinked coacervate and the ... -
Polymeric Nanoparticles
(Springer Nature, 2013)Self-assembling polymers, which are either amphiphilic block copolymers with hydrophobic and hydrophilic blocks, hydrophilic polymer backbones substituted with hydrophobic units or polymers with a low aqueous solubility, ... -
Polymers exhibiting lower critical solution temperatures as a route to thermoreversible gelators for healthcare
(2020-11-20)The ability to trigger changes to material properties with external stimuli, so-called “smart” behavior, has enabled novel technologies for a wide range of healthcare applications. Response to small changes in temperature ... -
Polymorphic control of inhalation microparticles prepared by crystallization
(2008-09-01)Milling processes are known to cause polymorphic transition in enantiotropic systems and the micronization process employed to produce microparticles for inhalation formulations has been reported to result in solid-state ... -
Polymorphisms of the cannabinoid 1 receptor gene and cognitive impairment in multiple sclerosis
(2008)Cognitive impairment occurs in 45—65% of multiple sclerosis (MS) patients. The cannabinoid system may potentially be neuroprotective in MS. We examined the relationship between polymorphisms of the CNR1 gene and ... -
Polymycovirus Infection Sensitizes Aspergillus fumigatus for Antifungal Effects of Nikkomycin Z
(2023-01-10)Infection with Aspergillus fumigatus polymycovirus 1 (AfuPmV-1) weakens resistance of Aspergillus fumigatus common reference strain Af293 biofilms in intermicrobial competition with Pseudomonas aeruginosa. We compared the ... -
The polymycovirus-mediated growth enhancement of the entomopathogenic fungus Beauveria bassiana is dependent on carbon and nitrogen metabolism
(2021-02-02)Polymycoviridae is a growing family of mycoviruses whose members typically have non-conventional capsids and multi-segmented, double-stranded (ds) RNA genomes. Beauveria bassiana polymycovirus (BbPmV) 1 is known to enhance ... -
Polymyxa graminis and the cereal viruses it transmits : a research challenge
(2003-09)Polymyxa graminis is a eukaryotic obligate biotrophic parasite of plant roots that belongs to a poorly studied discrete taxonomic unit informally called the 'plasmodiophorids'. P. graminis is nonpathogenic, but has the ... -
The polypeptide components of the parasporal fibres of Pasteuria penetrans
(2002-03)A variety of treatments were tested for their ability to solubilize the parasporal fibres from Pasteuria penetrans, a parasite of some plant-parasitic nematodes. Selective solubilization of the parasporal fibres resulted ... -
Polyphenols
(Willey-Blackwell, Oxford, UK, 2012) -
The Polysemy View of Pain
(2023-02-28)Philosophers disagree about what the folk concept of pain is. This aricle criticises existing theories of the folk concept of pain, that is, the mental view, the bodily view, and the recently proposed polyeidic view. It ...