dc.contributor.author | Whitfield, P. J. | |
dc.contributor.author | Bartlett, A. | |
dc.contributor.author | Khammo, N. | |
dc.contributor.author | Brain, A.P.R. | |
dc.contributor.author | Brown, Marc | |
dc.contributor.author | Marriott, C. | |
dc.contributor.author | Clothier, R. | |
dc.date.accessioned | 2013-06-06T07:30:51Z | |
dc.date.available | 2013-06-06T07:30:51Z | |
dc.date.issued | 2003-02 | |
dc.identifier.citation | Whitfield , P J , Bartlett , A , Khammo , N , Brain , A P R , Brown , M , Marriott , C & Clothier , R 2003 , ' Delayed tall loss during the invasion of human skin by schistosome cercariae ' , Parasitology , vol. 126 , no. 2 , pp. 135-140 . https://doi.org/10.1017/S0031182002002676 | |
dc.identifier.issn | 0031-1820 | |
dc.identifier.uri | http://hdl.handle.net/2299/10725 | |
dc.description.abstract | Schistosomiasis is initiated when cercarial larvae invade human skin. Contrary to long-held assumptions, most cercariae of Schistosoma mansoni do not shed their propulsive tails as they penetrate. Scanning electron microscopy studies and infection experiments with entire human skin and differentiated, stratum corneum-like, human keratinocyte cultures, have shown that most cercarial tails enter the skin along with their bodies. We propose that this behaviour is an adaptive trait linked with concomitant immunity. | en |
dc.format.extent | 6 | |
dc.format.extent | 171318 | |
dc.language.iso | eng | |
dc.relation.ispartof | Parasitology | |
dc.subject | schistosoma mansoni | |
dc.subject | tail loss | |
dc.subject | cercariae | |
dc.subject | invasion | |
dc.subject | concomitant immunity | |
dc.subject | MANSONI | |
dc.subject | IMMUNITY | |
dc.subject | CELLS | |
dc.title | Delayed tall loss during the invasion of human skin by schistosome cercariae | en |
dc.contributor.institution | Department of Pharmacy | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Health & Human Sciences Research Institute | |
dc.contributor.institution | Centre for Research into Topical Drug Delivery and Toxicology | |
dc.contributor.institution | Pharmaceutics | |
dc.contributor.institution | Skin and Nail Group | |
dc.contributor.institution | Airway Group | |
dc.contributor.institution | Bioadhesive Drug Delivery Group | |
dc.contributor.institution | Nanopharmaceutics | |
dc.contributor.institution | Pharmaceutical Analysis and Product Characterisation | |
dc.description.status | Peer reviewed | |
rioxxterms.versionofrecord | 10.1017/S0031182002002676 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |