dc.contributor.author | Yousif, Nada | |
dc.contributor.author | Pavese, Nicola | |
dc.contributor.author | Naushahi, Mohammad J | |
dc.contributor.author | Nandi, Dipankar | |
dc.contributor.author | Bain, Peter G | |
dc.date.accessioned | 2017-09-14T16:46:03Z | |
dc.date.available | 2017-09-14T16:46:03Z | |
dc.date.issued | 2014-01-02 | |
dc.identifier.citation | Yousif , N , Pavese , N , Naushahi , M J , Nandi , D & Bain , P G 2014 , ' Reversing the polarity of bipolar stimulation in deep brain stimulation for essential tremor : a theoretical explanation for a useful clinical intervention ' , Neurocase , vol. 20 , no. 1 , pp. 10-17 . https://doi.org/10.1080/13554794.2012.713495 | |
dc.identifier.issn | 1355-4794 | |
dc.identifier.uri | http://hdl.handle.net/2299/19412 | |
dc.description | Nada Yousif, et al, 'Reversing the polarity of bipolar stimulation in deep brain stimulation for essential tremor: A theoretical explanation for a useful clinical intervention', Neurocase, Vol. 20 (1): 10-17, September 2012, doi: http://dx.doi.org/10.1080/13554794.2012.713495. | |
dc.description.abstract | The quadripolar electrodes used for deep brain stimulation are designed to give flexibility in contact configuration, optimize therapeutic effect, and minimize side-effects. A patient with essential tremor did not tolerate a bipolar setting due to the emergence of a pulling sensation in her face. However, when the polarity of the contacts was reversed, a 70% higher voltage was tolerated. Using an electric field model, we predicted that this effect was due to the proximity of the topmost contact to the internal capsule. Post-operative imaging supported this prediction. These results demonstrate how a multi-disciplinary approach allows us to optimize parameter settings. | en |
dc.format.extent | 8 | |
dc.language.iso | eng | |
dc.relation.ispartof | Neurocase | |
dc.subject | Deep Brain Stimulation | |
dc.subject | Essential Tremor | |
dc.subject | Female | |
dc.subject | Humans | |
dc.subject | Implantable Neurostimulators | |
dc.subject | Middle Aged | |
dc.subject | Models, Neurological | |
dc.title | Reversing the polarity of bipolar stimulation in deep brain stimulation for essential tremor : a theoretical explanation for a useful clinical intervention | en |
dc.contributor.institution | School of Physics, Engineering & Computer Science | |
dc.contributor.institution | Department of Engineering and Technology | |
dc.contributor.institution | Centre for Engineering Research | |
dc.contributor.institution | BioEngineering | |
dc.contributor.institution | Biocomputation Research Group | |
dc.description.status | Peer reviewed | |
dc.identifier.url | http://www.tandfonline.com/eprint/3mfVJ5Mxns97dUHS52Rq/full | |
rioxxterms.versionofrecord | 10.1080/13554794.2012.713495 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |