dc.contributor.author | Jemni, Monèm | |
dc.contributor.author | Zaman, Rashid | |
dc.contributor.author | Carrick, Frederick | |
dc.contributor.author | Clarke, Neil | |
dc.contributor.author | Marina, Michel | |
dc.contributor.author | Bottoms, Lindsay | |
dc.contributor.author | Mathharoo, Jagdeep | |
dc.contributor.author | Ramsbottom, Roger | |
dc.contributor.author | Gu, Yaodong | |
dc.contributor.author | Konukman, Ferman | |
dc.date.accessioned | 2023-07-11T19:30:00Z | |
dc.date.available | 2023-07-11T19:30:00Z | |
dc.date.issued | 2023-03-08 | |
dc.identifier.citation | Jemni , M , Zaman , R , Carrick , F , Clarke , N , Marina , M , Bottoms , L , Mathharoo , J , Ramsbottom , R , Gu , Y & Konukman , F 2023 , ' Exercise improves depression through positive modulation of Brain-Derived Neurotrophic Factor (BDNF). A review based on 100 manuscripts over 20 years ' , Frontiers in Plant Science , vol. 14 , 1102526 , pp. 1-20 . https://doi.org/10.3389/fphys.2023.1102526 | |
dc.identifier.issn | 1664-462X | |
dc.identifier.other | Jisc: 972778 | |
dc.identifier.uri | http://hdl.handle.net/2299/26499 | |
dc.description | © 2023 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/ | |
dc.description.abstract | The aim of this review was to explore the relevant neurobiology and the association between peripheral levels of brain-derived neurotrophic factor (BDNF) and acute and short to long-term exercise regimes, as well as its relation to depression and antidepressant treatment. A 20-years literature search was conducted. The screening process resulted in 100 manuscripts. Antidepressants as well as acute exercise, particularly high-intensity, elevates BDNF in healthy humans and clinical populations, as evidenced from aerobic and resistance-based studies. Although exercise is increasingly recognised in the management of depression, acute and short-term exercise studies have failed to establish a relationship between the severity of depression and changes in peripheral BDNF. The latter rapidly returns to baseline, possibly indicating a quick re-uptake by the brain, aiding its neuroplasticity functions. The timescale of administration needed for the antidepressants to stimulate biochemical changes is longer than similar increases with acute exercise. | en |
dc.format.extent | 20 | |
dc.format.extent | 1368981 | |
dc.language.iso | eng | |
dc.relation.ispartof | Frontiers in Plant Science | |
dc.subject | BDNF expression | |
dc.subject | depression treatment | |
dc.subject | exercise mode | |
dc.subject | neuroplasticity | |
dc.subject | physical activity intervention | |
dc.subject | Physiology | |
dc.subject | Physiology (medical) | |
dc.title | Exercise improves depression through positive modulation of Brain-Derived Neurotrophic Factor (BDNF). A review based on 100 manuscripts over 20 years | en |
dc.contributor.institution | Centre for Future Societies Research | |
dc.contributor.institution | Department of Psychology, Sport and Geography | |
dc.contributor.institution | Centre for Research in Psychology and Sport Sciences | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Centre for Applied Clinical, Health and Care Research (CACHE) | |
dc.contributor.institution | High Performance Sport Research Group | |
dc.contributor.institution | Exercise, Health and Wellbeing Research Group | |
dc.description.status | Peer reviewed | |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85150745430&partnerID=8YFLogxK | |
rioxxterms.versionofrecord | 10.3389/fphys.2023.1102526 | |
rioxxterms.type | Other | |
herts.preservation.rarelyaccessed | true | |