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Non-parametric algorithmic generation of neuronal morphologies
(2008-12)
Generation algorithms allow for the generation of Virtual Neurons (VNs) from a small set of morphological properties. The set describes the morphological properties of real neurons in terms of statistical descriptors such ...
Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1 : implications for Parkinson's disease and protection by polyphenols
(2008-08-15)
Mechanisms of nigral cell injury in Parkinson's disease remain unclear, although a combination of increased oxidative stress, the formation of catecholamine-quinones and the subsequent formation of neurotoxic cysteinyl-c ...
Noncontact measurement of the local mechanical properties of living cells using pressure applied via a pipette
(2008)
Mechanosensitivity in living biological tissue is a study area of increasing importance, but investigative tools are often inadequate. We have developed a noncontact nanoscale method to apply quantified positive and negative ...