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Now showing items 161-170 of 380
Patterns of disease progression in type 2 and 3 SMA : Implications for clinical trials
(2015-12-03)
The aim of the study was to establish 12-month changes in the Hammersmith Functional motor scale in a large cohort of SMA patients, to identify patterns of disease progression and the effect of different variables. 268 ...
Plasma Levels of Middle Molecules to Estimate Residual Kidney Function in Haemodialysis without Urine Collection
(2015-12-02)
BACKGROUND: Residual Kidney Function (RKF) is associated with survival benefits in haemodialysis (HD) but is difficult to measure without urine collection. Middle molecules such as Cystatin C and β2-microglobulin accumulate ...
Selective reporting of results in guidelines
(2015-12)
Taylor and Perera argue persuasively that the 2014 National Institute for Health and Care Excellence (NICE) schizophrenia guideline promotes cognitive–behavioural therapy (CBT) and other psychosocial interventions beyond ...
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
(2015-12-01)
Strategies aimed at mimicking or enhancing the action of the incretin hormone glucagon-like peptide 1 (GLP-1) therapeutically improve glucose-stimulated insulin secretion (GSIS); however, it is not clear whether GLP-1 ...
Insights into the experiences of patients with cancer in London : framework analysis of free-text data from the National Cancer Patient Experience Survey 2012/2013 from the two London Integrated Cancer Systems
(2015-10-19)
OBJECTIVE: To shed light on experiences of patients with cancer in London National Health Service (NHS) trusts that may not be fully captured in national survey data, to inform improvement action plans by these trusts. ...
The mortality and hospitalization rates associated with the long interdialytic gap in thrice-weekly hemodialysis patients
(2015-09-30)
Excess mortality and hospitalization have been identified after the 2-day gap in thrice-weekly hemodialysis patients compared with 1-day intervals, although findings vary internationally. Here we aimed to identify factors ...
Appropriate and inappropriate influences on outpatient discharge decision making in dermatology : a prospective qualitative study
(2015-09-01)
BACKGROUND: Outpatient discharge decision making in dermatology is poorly understood. OBJECTIVE: To identify the influences on clinicians' thought processes when making discharge decisions in dermatology outpatient clinics. ...
Mental Representations of Weekdays
(2015-08-19)
Keeping social appointments involves keeping track of what day it is. In practice, mismatches between apparent day and actual day are common. For example, a person might think the current day is Wednesday when in fact it ...
After critical care : patient support after critical care. A mixed method longitudinal study using email interviews and questionnaires
(2015-08-01)
PURPOSE: To explore experiences and needs over time, of patients discharged from ICU using the Intensive Care Experience (ICE-q) questionnaire, Hospital Anxiety and Depression Scale (HADS) and EuroQoL (EQ-5D), associated ...
Proprioception in motor learning: : lessons from a deafferented subject
(2015-08-01)
Proprioceptive information arises from a variety of channels, including muscle, tendon, and skin afferents. It tells us where our static limbs are in space and how they are moving. It remains unclear however, how these ...