- UHRA Home
- Browsing by Author
Browsing by Author "Centre for Health Services and Clinical Research"
Now showing items 101-120 of 1037
-
Cannabinoid signalling in TNF-alpha induced IL-8 release
Mormina, M. E.; Thakur, S.; Molleman, A.; Whelan, C.J.; Baydoun, A. R. (2006) -
Cannabis; epidemiological, neurobiological and psychopathological issues: an update
De Luca, Maria Antonietta; Di Chiara, Gaetano; Cadoni, Cristina; Lecca, Daniele; Orsolini, Laura; Papanti, Duccio; Corkery, John; Schifano, Fabrizio (2017-04-13)Cannabis is the illicit drug with both the largest current levels of consumption and the highest reported lifetime prevalence levels in the world. Across different countries, the prevalence of cannabis use varies according ... -
Captagon: Use and Trade in the Middle East
Al-Imam, Ahmed; Santacroce, Rita; Roman-Urrestarazu, Andres; Chilcott, Robert; Martinotti, G.; Bersani, Giuseppe; Corazza, Ornella (2017-05-31)Fenetheylline, a psychostimulant drug, often branded as Captagon, is a combination of amphetamine and theophylline. Since the cessation of its legal production in 1986, counterfeited products have been produced illicitly ... -
Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: A systematic review and meta-analysis
Navarese, Eliano P; Lansky, Alexandra; Kereiakes, Dean; Kubica, Jacek; Gurbel, Paul A; Gorog, Diana; Valgimigli, Marco; Curzen, Nick; Kandzari, David. E.; Bonaca, Marc; Brouwer, Marc; Umińska, Julia M; Jaguszewski, Milosz; Raggi, Paolo; Waksman, Ron; Leon, Martin B.; Wijns, William; Andreotti, Felicita (2021-05-18)Aims:The value of elective coronary revascularisation plus medical therapy over medical therapy alone in managing stable patients with coronary artery disease is debated. We reviewed all trials comparing the two strategies ... -
Cardiovascular disease and COVID-19: a position paper from the ESC Working Group on Coronary Pathophysiology & Microcirculation, ESC Working Group on Thrombosis and the Association for Acute CardioVascular Care (ACVC), in collaboration with the European Heart Rhythm Association (EHRA)
Cenko, Edino; Badimon, L; Bugiardini, Raffaele; Claeys, Marc; de Luca, Giuseppe; Wit, Cor de; Derumeaux, Geneviève; Dorobantu, Maria; Duncker, Dirk; Eringa, Etto; Gorog, Diana; Hassager, Christian; Heinzel, Frank; Huber, Kurt; Manfrini, Olivia; Milicic, Davor; Oikonomou, Evangelos; Padro, Teresa; Trifunovic-Zamaklar, Danijela; Vasilejevic-Pokrajcic, Zorana; Vavlukis, Marija (2021-09-16)The cardiovascular system is significantly affected in coronavirus disease-19 (COVID-19). Microvascular injury, endothelial dysfunction and thrombosis resulting from viral infection or indirectly related to the intense ... -
Care pathways for the identification and management of depression in patients with chronic kidney disease: a rapid scoping review
Hall, Natalie; Pearce, Christina; Hudson, Joanna; Farrington, Kenneth; Wellsted, David; Jones, Julia; Sharma, Shivani; Norton, Sam; Ormandy, Paula; Palmer, Nick; Chilcot, Joe (2021-11-11)Depression is highly prevalent across the spectrum of Chronic Kidney Disease (CKD) and related to poor clinical outcomes. There is limited evidence regarding the most effective and acceptable interventions to manage ... -
Carfentanil on the darknet : Potential scam or alarming public health threat?
Negri, Attilio; Townshend, Honor; McSweeney, Tim; Angelopoulou, Olga; Prilutskaya, Mariya; Bowden-Jones, Owen; Corazza, Ornella (2021-05)Background: In an age of global insecurity, highly potent synthetic drugs have become a major public health issue. Their online advertisement and sale are facilitated by surface web, darknet markets and social media fuelling ... -
A cellulose-based bioassay for the colorimetric detection of pathogen DNA
Saikrishnan, Deepika; Goyal, Madhu; Rossiter, Sharon; Kukol, A. (2014-12-01)Cellulose-paper-based colorimetric bioassays may be used at the point of sampling without sophisticated equipment. This study reports the development of a colorimetric bioassay based on cellulose that can detect pathogen ... -
Challenges Faced by the Biopharmaceutical Industry in the Development and Marketing Authorization of Biosimilar Medicines in BRICS-TM Countries: An Exploratory Study
Rahalkar, Hasumati; Sheppard, Alan; Lopez-Morales, Carlos Augusto; Lobo, Luciano; Salek, Sam (2021-07-22)Abstract: Background: Biosimilars are expected to emerge as a rapidly growing segment of the biopharmaceutical industry. However, the biosimilar industry faces multiple challenges and obstacles in developing and marketing ... -
Changes to Physical Activity, Sitting Time, Eating Behaviours and Barriers to Exercise during the First COVID-19 ‘Lockdown’ in an English Cohort
Kass, Lindsy; Desai, Terun; Sullivan, Keith; Muniz, Daniel; Wells, Amy (2021-09-24)This study aimed to determine the effect of the first English national COVID-19 lockdown on physical activity (PA), sitting time, eating behaviours and body mass in an adult cohort. This was further examined to determine ... -
Changing Trends in the Use of Kratom (Mitragyna speciosa) in Southeast Asia
Singh, D; Narayanan, S; Vicknasingam, B; Corazza, Ornella; Santacroce, Rita; Roman-Urrestarazu, Andres (2017-06-28)Objective: Kratom (Mitragyna speciosa. Korth) is an indigenous medicinal plant of Southeast Asia. This review paper aims to describe the trends of kratom use in Southeast Asia, particularly, in Malaysia and Thailand, where ... -
Characterisation and localisation of [3H]2-(2-benzofuranyl)-2-imidazoline binding in rat brain : a selective ligand for imidazoline I2 receptors
Lione, Lisa; Nutt, D.J.; Hudson, A.L. (1998-07) -
Characterisation of chemical composition and structural features of novel antimicrobial nanoparticles
Ren, Guogang; Calvo-Castro, Jesus; Ciric, Lena; Edirisinghe, Mohan; Cloutman-Green, Elaine; Illangakoon, Upulitha Eranka; Kang, Qiang; Mahalingam, Suntharavathanan; Matharu, Rupy Kaur; Wilson, Rory M; Cheong, Yuen Ki (2017-06-23)Three antimicrobial nanoparticle types (AMNP0, AMNP1 and AMNP2) produced using the TesimaTM thermal plasma technology were investigated and their compositions determined using a combination of analytical methods. Scanning ... -
Characteristics of deaths associated with kratom use
Corkery, John; Streete, Peter; Claridge, Hugh; Goodair, Christine; Papanti, Duccio G.; Orsolini, Laura; Schifano, Fabrizio; Sikka, Kanav; Körber, Sophie; Hendricks, Amy (2019-09-01)Background: Kratom (Mitragyna speciosa Korth) use has increased in Western countries, with a rising number of associated deaths. There is growing debate about the involvement of kratom in these events. Aims: This study ... -
The characteristics of deaths involving kratom in the United Kingdom and elsewhere
Corkery, John; Claridge, Hugh; Goodair, Christine; Papanti, Duccio; Orsolini, Laura; Koerber, Sophie; Schifano, Fabrizio (2016-05-31) -
Characteristics of Frailty in Haemodialysis Patients
Hendra, Heidy; Sridharan, Sivakumar; Farrington, Ken; Davenport, Andrew (2022-05-06)Background: Both frailty and cachexia increase mortality in haemodialysis (HD) patients. The clinical frailty score (CFS) is a seven-point scale and less complex than other cachexia and frailty assessments. We wished to ... -
Characterization of imidazoline receptors by radioligand binding
Hudson, A.L.; Lione, Lisa (Humana Press, 1999) -
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation
Lione, Lisa; Carter, R. J.; Humby, T.; Mangiarini, L.; Mahal, A.; Bates, G. P.; Dunnett, S.B.; Morton, A. J. (1999-04-15)Transgenic mice expressing exon 1 of the human Huntington's disease (HD) gene carrying a 141-157 CAG repeat (line R6/2) develop a progressive neurological phenotype with motor symptoms resembling those seen in HD. We have ... -
Childhood trauma and schizotypy in non-clinical samples: A systematic review and meta-analysis
Toutountzidis, Diamantis; Gale, Tim M.; Irvine, Karen; Sharma, Shivani; Laws, Keith R. (2022-06-29)The association of early life adversities and psychosis symptoms is well documented in clinical populations; however, whether this relationship also extends into subclinical psychosis remains unclear. In particular, are ... -
Citizen Consultation on Problematic Usage of the Internet: Ethical Considerations and Empirical Insights from Six Countries
Gjoneska, Biljana; Jones, Julia; Vella, Anna Maria; Bonanno, Philip; Flora, Katerina; Fontalba-Navas, Andres; Hall, Natalie; Ignjatova, Liljana; Kirtava, Zviad; Moreno Sanjuan, Daniel; Piedade Vaz-Rebelo, Maria; Sales, Celia M (2021-04-01)Scientists and citizens can work together to improve the collective well-being, if citizens are inspired to help the advancement of science, and researchers motivated to listen to the voices of citizens. The benefits of ...