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Browsing by Author "Centre for Lifespan and Chronic Illness Research"
Now showing items 101-120 of 153
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The patients' experiences of their chronic non-malignant pain
Seers, K.; Friedli, K. (1996-12)This paper reports the results of a study which investigated the experiences of 75 people with chronic non-malignant pain.People with chronic non-malignant pain can find that traditional medical techniques do not help their ... -
Perfusion CT assessment of the colon and rectum : Feasibility of quantification of bowel wall perfusion and vascularization
Khan, Sairah; Goh, Vicky; Tam, Emily; Wellsted, D.; Halligan, Steve (2012)The aim was to determine the feasibility of vascular quantification of the bowel wall for different anatomical segments of the colorectum. Following institutional ethical approval and informed consent, 39 patients with ... -
A Phase I Trial of Radioimmunotherapy with 131I-A5B7 Anti-CEA Antibody in Combination with Combretastatin-A4-Phosphate in Advanced Gastrointestinal Carcinomas
Meyer, T.; Gaya, A.M.; Dancey, G.; Stratford, M.R.L.; Othman, S.; Sharma, S.; Wellsted, D.; Taylor, N.J.; Stirling, J.J.; Poupard, L.; Folkes, L.K.; Chan, P.S.; Pedley, R.B.; Chester, K.A.; Owen, K.; Violet, J.A.; Malaroda, A.; Green, A.J.; Buscombe, J.; Padhani, A.R.; Rustin, G.J.; Begent, R.H. (2009)Purpose: In preclinical models, radioimmunotherapy with 131I-A5B7 anti–carcinoembryonic antigen (CEA) antibody (131I-A5B7) combined with the vascular disruptive agent combretastatin-A4-phosphate (CA4P) produced cures unlike ... -
Physical activity and hypertension in South African adults
Ware, L.J.; Rennie, Kirsten; Gafane, L; Collard, Jade; Nell, T.; Shutte, Aletta (2014)Estimates suggest that approximately 6-million South Africans have hypertension, with half classified as stage 1 (mild). Mindful of the cost of lifelong drug therapy, the South African Hypertension Society guidelines suggest ... -
A pilot study of the epilepsy risk awareness checklist (ERAC) in people with epilepsy and learning disabilities
Cole, C.; Pointu, A.; Wellsted, D.; Angus-Leppan, H. (2010)Purpose: People with epilepsy are at risk of injury, and protection from potential dangers must be balanced against the need for autonomy. We developed an epilepsy risk awareness checklist (ERAC) as a tool to assess potential ... -
A pilot study to investigate the effect of using current, reported and surrogate height measurements in nutritional screening of the elderly
Butler, Rose; McClinchy, Jane; Rennie, Kirsten (2013)Adults naturally lose height as part of the aging process. This pilot study was undertaken following the observation in clinical practice that when older people were asked how tall they were, they invariably reported the ... -
Pragmatic use of Language by Children who develop Schizophrenia in adult life
Done, D.J.; Leinonen, Eeva (2013-06)At eleven years of age all children in a UK national birth cohort wrote short stories about the life they expected to be leading at age 25. Using a data linkage exercise, we identified those who later developed schizophrenia ... -
Predicting residual kidney function in hemodialysis patients using serum β-trace protein and β2-microglobulin
Wong, Jonathan; Sridharan, Sivakumar; Berdeprado, Jocelyn; Viljoen, Adie; Vilar Hall, Enric; Wellsted, David; Farrington, Kenneth (2016-02-16)Residual kidney function (RKF) contributes significant solute clearance in hemodialysis patients. Kidney Diseases Outcomes Quality Initiative (KDOQI) guidelines suggest that hemodialysis dose can be safely reduced in those ... -
Prediction Error in Reinforcement Learning : A Meta-analysis of Neuroimaging studies
Garrison, J.; Erdeniz, B.; Done, D.J. (2013-08)Activation likelihood estimation (ALE) meta-analyses were used to examine the neural correlates of prediction error in reinforcement learning. The findings are interpreted in the light of current computational models of ... -
Prenatal exposure to influenza does not cause schizophrenia
Crow, T.J.; Done, D.J. (1992) -
Primary Colorectal Cancer : Use of Kinetic Modeling of Dynamic Contrast-enhanced CT Data to Predict Clinical Outcome
Koh, Tong San; Ng, Quan Sing; Thng, Choon Hua; Kwek, Jin Wei; Kozarski, Robert; Goh, Vicky (2013-04)To compare four different tracer kinetic models for the analysis of dynamic contrast material–enhanced computed tomographic (CT) data with respect to the prediction of 5-year overall survival in primary colorectal cancer -
Primary Esophageal Cancer Heterogeneity as a Potential Prognostic Biomarker in Patients Treated with Definitive Chemoradiation
Yip, Connie; Landau, David; Kozarski, Robert; Ganeshan, Balaji; Thomas, R.; Michaelidou, A.; Goh, Vicky (2014-01)To determine the association between tumor heterogeneity, morphologic tumor response, and overall survival in primary esophageal cancer treated with chemotherapy and radiation therapy (CRT) -
Psychological support for patients having breast cancer surgery : Study had methodological flaws
Friedli, K; King, M (1996-08-10) -
Psychological treatments and their evaluation
Friedli, K; King, Michael B. (1998-05) -
Quality of Life and Survival in Patients with Advanced Kidney Failure Managed Conservatively or by Dialysis
Da Silva-Gane, Maria; Wellsted, D.; Greenshields, Hannah; Norton, Sam; Chandna, Shahid M.; Farrington, Ken (2012-12-07)BACKGROUND AND OBJECTIVES: Benefits of dialysis in elderly dependent patients are not clearcut. Some patients forego dialysis, opting for conservative kidney management (CKM). This study prospectively compared quality of ... -
Quantitative assessment of colorectal cancer tumor vascular parameters by using perfusion CT: influence of tumor region of interest
Goh, Vicky; Halligan, Steve; Gharpuray, Anita; Wellsted, D.; Sundin, Josefin; Bartram, Clive I (2008)To prospectively determine whether position and size of tumor region of interest (ROI) influence estimates of colorectal cancer vascular parameters at computed tomography (CT). -
Quantitative helical dynamic contrast enhanced computed tomography assessment of the spatial variation in whole tumour blood volume with radiotherapy in lung cancer
Ng, Q-S.; Goh, V.; Milner, J.; Sundin, J.; Wellsted, D.; Saunders, M.I.; Hoskin, P.J. (2010)We aim to assess the spatial distribution of blood volume (BV) in whole lung tumours in patients undergoing radiotherapy using helical dynamic contrast enhanced computed tomography (DCE-CT), and to determine whether ... -
Randomised controlled assessment of non-directive psychotherapy versus routine general-practitioner care
Friedli, K.; King, M. B.; Lloyd, M.; Horder, J. (1997-12-06)Background We compared the efficacy of and patients' satisfaction with general-practice-based psychotherapists with those of general practitioners in providing treatment to people with emotional difficulties. Methods We ... -
Rates and Determinants of Uptake and Use of an Internet Physical Activity and Weight Management Program in Office and Manufacturing Work Sites in England: Cohort Study
Ware, L.J.; Hurling, R.; Batavelijic, O.; Fairley, B.W.; Hurst, T.; Murray, P.; Rennie, K.L.; Tomkins, C.E.; Finn, A.; Cobain, M.; Pearson, D.A.; Foreyt, J.P. (2008) -
Relationship between human tumour angiogenic profile and combretastatin-induced vascular shutdown : an exploratory study
Gaya, A.M.; Daley, F.; Taylor, N. J.; Tozer, G.; Qureshi, U; Padhani, A.; Pedley, R. Barbara; Begent, R; Wellsted, D.; Stirling, J J; Rustin, G (2008)Combretastatin-A4-phosphate (CA4P) acts most effectively against immature tumour vasculature. We investigated whether histological angiogenic profile can explain the differential sensitivity of human tumours to CA4P, by ...