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Now showing items 181-200 of 1037
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Copper (II) mediated arylation with aryl boronic acids for the N-derivatization of pyrazole libraries
Rossiter, S.; Woo, C.K.; Hartzoulakis, B.; Wishart, G.; Stanyer, L.; Labadie, J.W.; Selwood, D.L. (2004)A N-derivatized 3-dimethylaminopropyloxypyrazole library was prepared using solution-phase parallel synthesis. The library was designed using physicochemical constraints designed to remove non-membrane-permeable molecules. ... -
Correlating the Dermatology Life Quality Index with psychiatric measures: A systematic review.
Ali, FM; Johns, Nutjaree; Salek, Mir-Saeed Shayegan; Finlay, Andrew Y. (2018-11-01)Skin conditions may have a major impact on the psychologic well-being of patients, ranging from depression to anxiety. The Dermatology Life Quality Index (DLQI) is the most commonly used quality of life tool in dermatology, ... -
Could Cariprazine Be a Possible Choice for High Functioning Autism? A Case Report
Miuli, Andrea; Marrangone, Carlotta; Di Marco, Ornella; Pasino, Arianna; Stigliano, Gianfranco; Mosca, Alessio; Pettorruso, Mauro; Schifano, Fabrizio; Martinotti, Giovanni (2023-12-01)This case report was conducted by searching for the following keywords on PubMed: High Functioning Autism, Autism Spectrum Disorder, cariprazine, aripiprazole, partial agonist antipsychotic, DRD2/DRD3. High Functioning ... -
Covid-19 pandemic impact on substance misuse: a social media listening, mixed method analysis.
Arillotta, Davide; Guirguis, Amira; Corkery, John Martin; Scherbaum, Norbert; Schifano, Fabrizio (2021-07-09)The restrictive measures adopted during the COVID-19 pandemic modified some previously consolidated drug use patterns. A focus on social networks allowed drug users to discuss, share opinions and provide advice during a ... -
COVID-19: The hidden impact on mental health and drug addiction
Chiappini, Stefania; Guirguis, Amira; John, Ann; Corkery, John; Schifano, Fabrizio (2020-07-29)There is concern the Coronavirus Disease (COVID)-19 pandemic is having a negative impact on the mental health of the general population through a range of suggested mechanisms: fear, uncertainty, and anxiety; social ... -
Criteria for and Appropriateness of Renal Transplantation in Elderly Patients With End-Stage Renal Disease : A Literature Review and Position Statement on Behalf of the European Renal Association-European Dialysis and Transplant Association Descartes Working Group and European Renal Best Practice
Segall, Liviu; Nistor, Ionuţ; Pascual, Julio; Mucsi, Istvan; Guirado, Lluis; Higgins, Robert; Van Laecke, Steven; Oberbauer, Rainer; Van Biesen, Wim; Abramowicz, Daniel; Gavrilovici, Cristina; Farrington, Ken; Covic, Adrian (2016-10-01)During the last 20 years, waiting lists for renal transplantation (RT) have grown significantly older. However, elderly patients (ie ≥65 years of age) are still more rarely referred or accepted to waiting lists and, if ... -
A cross sectional study of impact and clinical risk factors of antipsychotic-induced OCD
Biria, Marjan; Huang, Fiona-Xiaofei; Worbe, Yulia; Fineberg, Naomi; Robbins, Trevor W.; Fernandez-Egea, Emilio (2019-08-01)A large proportion of schizophrenia patients treated with second generation antipsychotics will develop Obsessive Compulsive Disorder (OCD). However, there are few studies about the impact of this comorbidity and who is ... -
Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium
Gorog, Diana A.; Storey, Robert F.; Gurbel, Paul A.; Tantry, Udaya S.; Berger, Jeffrey S.; Chan, Mark Y.; Duerschmied, Daniel; Smyth, Susan S.; Parker, William A.E.; Ajjan, Ramzi A.; Vilahur, Gemma; Badimon, Lina; Berg, Jurrien M.ten; Cate, Hugo ten; Peyvandi, Flora; Wang, Taia T.; Becker, Richard C. (2022-07)Coronavirus disease 2019 (COVID-19) predisposes patients to thrombotic and thromboembolic events, owing to excessive inflammation, endothelial cell activation and injury, platelet activation and hypercoagulability. Patients ... -
Current Practices and the Future of Robotic Surgical Training
Sinha, Ankit; West, Alexander; Vasdev, Nikhil; Sooriakumaran, Prasanna; Rane, Abhay; Dasgupta, Prokar; McKirdy, Michael (2023-03-15)Introduction: This study reviews the current state of robotic surgery training for surgeons, including the various curricula, training methods, and tools available, as well as the challenges and limitations of these. ... -
Current Regulatory Requirements for Biosimilars in Six Member Countries of BRICS-TM: Challenges and Opportunities
Rahalkar, Hasumati; Sheppard, Alan; Santos, Gustavo Mendes Lima; Dasgupta, Chitralekha; Perez-Tapia, Sonia Mayra; Lopez-Morales, Carlos A.; Salek, Sam (2021-09-09)Background: The aim of the study was to identify, interpret, and compare the current perspectives of regulatory agencies in six member countries of BRICS-TM (Brazil, Russia, India, China, South Africa, Turkey, and Mexico) ... -
Current role of cytoreductive nephrectomy in metastatic renal cell carcinoma
Van Praet, Charles; Slots, Charlotte; Vasdev, Nikhil; Rottey, Sylvie; Fonteyne, Valérie; Andras, Iulia; Albersen, Maarten; De Meerleer, Gert; Bex, Axel; Decaestecker, Karel (2021-02-01)Historically, immediate cytoreductive nephrectomy (CN) was considered the standard of care in patients with metastatic renal cell carcinoma (mRCC) who were fit enough to undergo surgery. Recently, 2 randomized controlled ... -
Cyberchondria as an emerging trans-diagnostic digital compulsive syndrome: An updated systematic review and clinical case report
Vismara, Matteo; Cinosi, Eduardo; Dell'Osso, Bernardo; Fineberg, Naomi (2019-07-06) -
The Dangerous use of Inhalants among Teens: a Case Report
Levari, Emerlinda; Stefani, Martina; Ferrucci, Roberta; Negri, Attilio; Corazza, Ornella (2021-03-20)The recreational use of inhalants among teenagers and other vulnerable individuals is a growing cause of concern for clinicians. Products, such as computer dusters and spray cleaners containing highly toxic compounds, such ... -
De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis.
Gorog, Diana; Ferreiro, Jose Luis; Ahrens, Ingo; Ako, Junya; Geisler, Tobias; Halvorsen, Sigrun; Huber, Kurt; Jeong, Young-Hoon; Navarese, Eliano P; Rubboli, Andrea; Sibbing, Dirk; Siller-Matula, Jolanta M; Storey, Robert F.; Tan, Jack W C; Berg, Jurrien M.ten; Valgimigli, Marco; Vandenbriele, Christophe; Lip, Gregory Y H (2023-07-20)Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y purinoceptor 12 (P2Y12) inhibitor (prasugrel or ... -
Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic
STARSurg Collaborative; COVIDSurg Collaborative (2021-11-13)Background: This study aimed to determine the impact of pulmonary complications on death after surgery both before and during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Methods: This was a ... -
'Defining, measuring and monitoring Drug-Related Deaths in national and sub-national contexts: the example of the United Kingdom'
Corkery, John (Comité permanent de lutte à la toxicomanie, 2002-10) -
The definition of treatment resistance in anxiety disorders: a Delphi method-based consensus guideline
Domschke, Katharina; Seuling, Patrik D.; Schiele, Miriam A.; Bandelow, Borwin; Batelaan, Neeltje M.; Bokma, Wicher A.; Branchi, Igor; Broich, Karl; Burkauskas, Julius; Davies, Simon J.C.; Dell'Osso, Bernardo; Fagan, Harry; Fineberg, Naomi; Furukawa, Toshi A.; Hofmann, Stefan G.; Hood, Sean; Huneke, Nathan T.M.; Latas, Milan; Lidbetter, Nicky; Masdrakis, Vasilios; McAllister-Williams, R. Hamish; Nardi, Antonio E.; Pallanti, Stefano; Penninx, Brenda W.J.H.; Perna, Giampaolo; Pilling, Steve; Pini, Stefano; Reif, Andreas; Seedat, Soraya; Simons, Gemma; Srivastava, Shrikant; Steibliene, Vesta; Stein, Dan J.; Stein, Murray; Van Ameringen, Michael; van Balkom, Anton J.L.M.; van der Wee, Nic; Zwanzger, Peter; Baldwin, David S (2024-02-28)Anxiety disorders are very prevalent and often persistent mental disorders, with a considerable rate of treatment resistance which requires regulatory clinical trials of innovative therapeutic interventions. However, an ... -
Definition, assessment and management of frailty for people with intellectual disabilities: A scoping review.
Grohmann, Dominique; Wellsted, David; Mengoni, Silvana (2024-05)Background: People with intellectual disabilities may experience frailty earlier than the general population. This scoping review aimed to investigate how frailty is defined, assessed, and managed in adults with an ... -
Delayed radical prostatectomy for localised prostate cancer – A systematic review and meta-analysis for the COVID-19 Pandemic
Chan, Vinson Wai-Shun; Tan, Wei Shen; Asif, Aqua; Ng, Alexander; Gbolahan, Olayinka; Dinneen, Eion; To, Wilson; Kadhim, Hassan; Premchand, Melissa; Burton, Oliver; Koe, Jasmine Sze-Ern; Wang, Nicole; Leow, Jeffrey; Giannarini, Gianluca; Vasdev, Nikhil; Shariat, S. F.; Enikeev, Dmitry; Ng, Chi Fai; Teoh, Jeremy (2021-06-30)External factors, such as the coronavirus disease 2019 (COVID-19), can lead to cancellations and backlogs of cancer surgeries. The effects of these delays are unclear. This study summarised the evidence surrounding expectant ... -
Demethylation of 2,4-dimethoxquinolines: the synthesis of atanine
Jones, K.; Roset, X.; Rossiter, S.; Whitfield, P.J. (2003)