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Browsing by Author "Centre for Clinical Practice, Safe Medicines and Drug Misuse Research"
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'Bundle of fun' or 'bunch of problems'? : Case series of khat-related deaths in the UK
Corkery, John; Schifano, Fabrizio; Oyefeso, Adenekan; Ghodse, A. Hamid; Tonia, Thomy; Naidoo, Vinesha; Button, Jennifer (2011)Twenty million people worldwide use khat (Catha edulis). Previously confined to Eastern Africa and Arabia, consumption is spreading to other regions. Chewing khat leaves releases the stimulants cathinone and cathine. Khat ... -
Bupropion perceived as a stimulant by two patients with a previous history of cocaine misuse
Vento, A.E.; Schifano, Fabrizio; Gentili, Federica; Pompei, Francesco; Corkery, John; Kotzalidis, Georgios D.; Girardi, Paolo (2013-12)Background and objective. Despite animal studies having shown a generalisation of the bupropion cue to cocaine, this drug has been used in cocaine abuse with mixed results. We here aimed at describing two cases which ... -
Burnout, coping and job satisfaction in service staff treating opioid addicts : from Athens to Zurich
Volker, R.; Bernhard, B.; Kokkevi, A.; Schifano, Fabrizio; Room, R.; Palm, J.; Stohler, R.; DiFuria, L.; Rehm, J.; Holscher, F.; Schwarzer, C. (2010)The Treatment-systems Research on European Addiction Treatment study (TREAT-project) is a longitudinal multicenter study on predominantly opioid-dependent patients and their health-care system in six European cities. As ... -
Can mobile phone technology support a rapid sharing of information on Novel Psychoactive Substances among health and other professionals internationally?
Simonato, Pierluigi; Bersani, Francesco Saverio; Santacroce, Rita; Cinosi, Eduardo; Schifano, Fabrizio; Bersani, Giuseppe; Martinotti, Giovanni; Corazza, Ornella (2017-06-28)Background The diffusion of Novel Psychoactive Substances (NPSs), combined with the ability of the Internet to act as an online marketplace, has led to unprecedented challenges for governments, health agencies, and substance ... -
Can reinforcement-based interventions to reduce drug use successfully be adapted to routine opioid maintenance treatment?
Specka, Michael; Öning, Antje; Kluwig, Jürgen; Schifano, Fabrizio; Banger, Markus; Lange, Wolfgang; Lax, Hildegard; Marrziniak, Bärbel; Schüngel, Claudia; Scherbaum, Norbert (2013-12-01)Introduction. Comorbid substance related disorders are a major health problem for patients in opioid maintenance treatment (OMT). It was investigated whether a reinforcement scheme adapted to the regulatory and financial ... -
Cannabis; epidemiological, neurobiological and psychopathological issues: an update
De Luca, Maria Antonietta; Di Chiara, Gaetano; Cadoni, Cristina; Lecca, Daniele; Orsolini, Laura; Papanti, Duccio; Corkery, John; Schifano, Fabrizio (2017-04-13)Cannabis is the illicit drug with both the largest current levels of consumption and the highest reported lifetime prevalence levels in the world. Across different countries, the prevalence of cannabis use varies according ... -
Carfentanil on the darknet : Potential scam or alarming public health threat?
Negri, Attilio; Townshend, Honor; McSweeney, Tim; Angelopoulou, Olga; Prilutskaya, Mariya; Bowden-Jones, Owen; Corazza, Ornella (2021-05)Background: In an age of global insecurity, highly potent synthetic drugs have become a major public health issue. Their online advertisement and sale are facilitated by surface web, darknet markets and social media fuelling ... -
Cathinone-related mortality: khat, mephedrone and related novel psychoactive substances and their role in deaths – the UK experience
Corkery, John (2012-03-12)This paper will present an overview of the work undertaken in the UK to establish a solid evidence base on the relationships between khat, mephedrone, and related novel psychoactive substances to mortality. The processes ... -
Changing Trends in the Use of Kratom (Mitragyna speciosa) in Southeast Asia
Singh, D; Narayanan, S; Vicknasingam, B; Corazza, Ornella; Santacroce, Rita; Roman-Urrestarazu, Andres (2017-06-28)Objective: Kratom (Mitragyna speciosa. Korth) is an indigenous medicinal plant of Southeast Asia. This review paper aims to describe the trends of kratom use in Southeast Asia, particularly, in Malaysia and Thailand, where ... -
Chapter 6: Health correlates and consequences
English, Layla; Corkery, John; Hope, Vivian (UK Focal Point on Drugs at Public Health England, 2013-12-16) -
Chapter 7: Responses to health correlates and consequences.
English, Layla; Hope, Vivian; Corkery, John (UK Focal Point on Drugs at Public Health England, 2013-12-16) -
Characteristics of deaths associated with kratom use
Corkery, John; Streete, Peter; Claridge, Hugh; Goodair, Christine; Papanti, Duccio G.; Orsolini, Laura; Schifano, Fabrizio; Sikka, Kanav; Körber, Sophie; Hendricks, Amy (2019-09-01)Background: Kratom (Mitragyna speciosa Korth) use has increased in Western countries, with a rising number of associated deaths. There is growing debate about the involvement of kratom in these events. Aims: This study ... -
The characteristics of deaths involving kratom in the United Kingdom and elsewhere
Corkery, John; Claridge, Hugh; Goodair, Christine; Papanti, Duccio; Orsolini, Laura; Koerber, Sophie; Schifano, Fabrizio (2016-05-31) -
Classification, location and legitimacy of web-based suppliers of Viagra to the UK
Gallagher, C. T. (2010-12-01)Objectives- To categorise online suppliers of Viagra based on their legal status, and to quantify the suppliers within each category. Methods- Google was used to search for websites offering to sell or supply either ... -
Clinical handover incident reporting in one UK general hospital
Pezzolesi, Cinzia; Schifano, Fabrizio; Pickles, John; Randell, William; Hussain, Zakar; Muir, Helen; Dhillon, S. (2010)To determine the prevalence and characteristics of clinical handover incidents that occurred across a medium-size UK hospital. -
Clinical pharmacy practice : Implications for pharmacy education in Belgium
Spinewine, A.; Dhillon, S. (2002-06-01)Belgian hospital pharmacy practice is in a process of transition, with the clinical role of the pharmacist being progressively developed. Knowledge and skills specific to clinical pharmacy (CP) will be required in the ... -
Combined NMDA Inhibitor Use in a Patient With Multisubstance-induced Psychotic Disorder
Caloro, Matteo; Calabrò, Giuseppa; de Pisa, Eleonora; Rosini, Enrico; Kotzalidis, Georgios D; Lonati, Davide; Locatelli, Carlo Alessandro; Papa, Pietro; Schifano, Fabrizio; Girardi, Paolo (2018-05-01): Novel psychoactive substance use is a major social concern. Their use may elicit or uncover unpredictably as yet undescribed clinical pictures. We aimed to illustrate a multisubstance use case indistinguishable from ... -
Commentary on: Attafi IM, Albeishy MY, Oraiby ME, Khardali IA, Shaikhain GA, Fageeh MM. Postmortem Distribution of Cathinone and Cathine in Human Biological Specimens in a Case of Death Associated with Khat Chewing. Arab J Forensic Sci Forensic Med. 2018 Jun 7;1(7).
Corkery, John; Schifano, Fabrizio; Guirguis, Amira (2019-12-31)The interpretation of post-mortem human tissue toxicology levels may be affected by the sampling site chosen. It is important to bear this in mind when looking at the psychoactive constituents of khat (Catha edulis Forsk.) ... -
Comparative Efficacy And Tolerability Of Antiepileptic Drugs For Refractory Epilepsy : A Systematic Review And Network Meta-Analysis And Network Meta Analysis
Bodalia, Pritesh N.; Grosso, Anthony M.; Sofat, Rajesh; Macallister, Raymond J.; Smeeth, Liam; Dhillon, S.; Casas, Juan-Pablo; Wonderling, David; Hingorani, A.D. (2010) -
Comparative Efficacy and Tolerability of Antiepileptic Drugs for Refractory Focal Epilepsy Systematic Review and Network Meta-Analysis reveals the need for long-term comparator trials
Bodalia, Pritesh N.; Grosso, Anthony M.; Sofat, Reecha; Macallister, Raymond J.; Smeeth, Liam; Dhillon, S.; Casas, Juan-Pablo; Wonderling, David; Hingorani, Aroon D. (2013)To evaluate the comparative efficacy (50% reduction in seizure frequency) and tolerability (premature withdrawal due to adverse events) of antiepileptic drugs (AEDs) for refractory epilepsy. METHODS: We searched Cochrane ...