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Now showing items 221-240 of 1038
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Development of the Paranormal and Supernatural Beliefs Scale using classical and modern test theory
Dean, Charlotte E; Akhtar, Shazia; Gale, Tim M; Irvine, Karen; Wiseman, Richard; Laws, Keith R (2021-06-23)Background: This study describes the construction and validation of a new scale for measuring belief in paranormal phenomena. The work aims to address psychometric and conceptual shortcomings associated with existing ... -
Development of the Pyruvate Kinase Deficiency Diary (PKDD) and Pyruvate Kinase Deficiency Impact Assessment (PKDIA): Disease-Specific Assessments
Salek, Sam (2019-12-27)INTRODUCTION: Currently recommended patient-reported outcome (PRO) measures for patients with pyruvate kinase (PK) deficiency are non-disease-specific. The PK Deficiency Diary (PKDD) and PK Deficiency Impact Assessment ... -
Diabetes confers in vitro calcific potential on serum which associates with in-vivo vascular calcification
Patidar, Ashish; Singh, Dhruv; Thakur, Shori; Winocour, Peter; Farrington, Kenneth; Baydoun, Anwar (2017-05-09)Although vascular calcification (VC) is prevalent in Type 2 diabetes mellitus (T2DM), underlying mechanisms remain unclear. Neither is it known whether T2DM confers calcific potential (CP) on serum, enabling it to induce ... -
Diabetes Self-management Apps : Systematic Review of Adoption Determinants and Future Research Agenda
Alaslawi, Hessah; Berrou, Ilhem; Al Hamid, Abdullah; Alhuwail, Dari; Aslanpour, Zoe (2022-07-28)Background: Most diabetes management involves self-management. Effective self-management of the condition improves diabetes control, reduces the risk of complications, and improves patient outcomes. Mobile apps for diabetes ... -
Diabetic dyslipidaemia is associated with alterations in eNOS, caveolin-1 and endothelial dysfunction in streptozotocin treated rats
Shamsaldeen, Yousif; Ugur, Rosemary; Benham, Christopher; Lione, Lisa (2018-07-01)Background: Diabetes is a complex progressive disease characterised by chronic hyperglycaemia and dyslipidaemia associated with endothelial dysfunction. Oxidised LDL (Ox-LDL) is elevated in diabetes and may contribute to ... -
Diabetic dyslipidaemia is associated with alterations in eNOS, caveolin-1 and endothelial dysfunction in streptozotocin treated rats : Supplement to Diabetes Metab Res Rev. 34(5):e2995.
Lione, Lisa; Benham, Christopher; Shamsaldeen, Yousif (Biomedical Advances, 2019-08-13)Background: Diabetes is a complex progressive disease characterised by chronic hyperglycaemia and dyslipidaemia associated with endothelial dysfunction. Oxidised LDL (Ox-LDL) is elevated in diabetes and may contribute to ... -
Differential effects of sertraline and cognitive behavioural therapy on behavioural inhibition in patients with obsessive compulsive disorder
Reid, Jemma E; Pellegrini, Luca; Drummond, Lynne; Varlakova, Yana; Shahper, Sonia; Baldwin, David S; Manson, Christopher; Chamberlain, Samuel R; Robbins, Trevor W; Wellsted, David; Fineberg, Naomi A (2024-04-02)Patients with obsessive compulsive disorder (OCD) randomised to sertraline, manualised cognitive behavioural therapy (CBT), or combination (sertraline + CBT), underwent cognitive assessment. Cognitive testing was conducted ... -
Differential modulation of motor neurons that innervate the same muscle but use different excitatory transmitters in Aplysia
Keating, Christopher; Lloyd, Philip (1999-10)The medial portion of intrinsic buccal muscle 3 (I3m) is innervated by two excitatory motor neurons, B3 and B9. B3 uses glutamate as its fast transmitter and expresses the neuropeptide FMRFamide, whereas B9 uses acetylcholine ... -
Differential release of dopamine by nitric oxide in subregions of rat caudate putamen slices
Iravani, Mahmoud M.; Millar, J.; Kruk, Z. L. (1998-11)Fast cyclic voltammetry was used to measure NO and dopamine (DA) simultaneously in rat caudate putamen (CPu) slices. Analysis of electrochemical signals obtained from mixtures of DA and NO showed that subtraction of either ... -
Differential sensitivities of rat striatal D-2 Dopamine autoreceptor sites
Iravani, Mahmoud M.; Kruk, Z. L. (1992-10) -
Differential-effects of Nifedipine on nerve-mediated and noradrenaline-evoked contractions of rat anococcygeus muscle
Iravani, Mahmoud M.; Zar, M. A. (1993-11-30)In rat anococcygeus muscle the inhibitory effect of nifedipine (0.01. 0.1, 1.0 and 10 muM) was determined on adrenergic twitches in response to electrical field stimulation (trains of 4 pulses, 0.1 ms pulse duration. 10 ... -
Dipendenze farmacologiche e comportamentali
Schifano, Fabrizio (Piccin Nuova Libraria, 2021-11-22) -
Direct effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin or dopamine release and uptake in the caudate putamen, nucleus accumbens, substantia nigra pars reticulate, and the dorsal raphe nucleus slices
Iravani, Mahmoud M.; Asari, D.; Patel, J.; Wieczorek, W. J.; Kruk, Z. L. (2000-06-15)We examined the effects of pressure ejected 3,4-methylenedioxymethamphetamine (MDMA) from a micropipette on direct chemically stimulated release, and on electrically stimulated serotonin (5-HT) or dopamine (DA) release in ... -
The dirty hand in the latex glove.” A study of hand hygiene compliance when gloves are worn.
Besser, Sarah Jane (2011-12-01)Background and objective. Wearing of gloves reduces transmission of organisms by healthcare workers’ hands but is not a substitute for hand hygiene. Results of previous studies have varied as to whether hand hygiene is ... -
Disciplinary Action Against UK Health Professionals for Sexual Misconduct: A Matter of Reputational Damage or Public Safety?
Gallagher, Cathal T.; Thaci, Jeta; Saadalla, Georgina; Mohamed, Nasteha; Ismail, Murwo M.; Gossel, Thelma; Attopley, Melissa; Thomas Gallagher, Cathal (2022-02-22)A B S T R A C T: The regulation of health care professionals in the United Kingdom (UK) falls under the authority of one of nine General Councils, each of which has a statutory duty to ensure the fitness to practice of a ... -
Discordant inflammation and pain in early and established rheumatoid arthritis : Latent Class Analysis of Early Rheumatoid Arthritis Network and British Society for Rheumatology Biologics Register data
McWilliams, Daniel F.; Ferguson, Eamonn; Young, Adam; Kiely, Patrick D.W.; Walsh, David A. (2016-12-13)Background: Rheumatoid arthritis (RA) disease activity is often measured using the 28-joint Disease Activity Score (DAS28). We aimed to identify and independently verify subgroups of people with RA that may be discordant ... -
Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis
Hartzoulakis, B.; Rossiter, S.; Gill, H.; Steinke, E.; Gane, P.J.; Hurtado-Guerrero, R.; Leiper, J.M.; Vallance, P.; Murray-Rust, J.; Selwood, D.L. (2007) -
Discovery of novel small molecule inhibitors of S100P, with in vitro anti-metastatic effects on pancreatic cancer cells
Camara, Ramatoulie; Ogbeni, Deborah; Gerstmann, Lisa; Ostovar, Mehrnoosh; Hurer, Ellie; Scott, Mark; Mahmoud, Nasir; Radon, Tomasz; Crnogorac-Jurcevic, Tatjana; Patel, Pryank; Mackenzie, Louise Susan; Chau, David; Kirton, Stewart; Rossiter, Sharon (2020-10-01)S100P, a calcium- binding protein, is known to advance tumor progression and metastasis in pancreatic and several other cancers. Herein is described the in silico identification of a putative binding pocket of S100P to ... -
Disease activity flares and pain flares in an early rheumatoid arthritis inception cohort; characteristics, antecedents and sequelae
McWilliams, Daniel F; Rahman, Shimin; James, Richard J E; Ferguson, Eamonn; Kiely, Patrick D W; Young, Adam; Walsh, David A (2019-11-18)Background: RA flares are common and disabling. They are described in terms of worsening inflammation but pain and inflammation are often discordant. To inform treatment decisions, we investigated whether inflammatory and ... -
Disorders Due to Addictive Behaviours and Impulse Control Disorders
Billieux, Joël; Fineberg, Naomi; King, Daniel L; Rumpf, Hans Jürgen (American Psychological Association, 2024-01-02)This chapter focuses on two groupings of disorders in the 11th revision of the International Classification of Diseases (ICD-11): disorders due to addictive behaviors—namely, gambling disorder and gaming disorder—and impulse ...