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Now showing items 41-60 of 1037
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Antimicrobial stewardship implementation before and during the COVID-19 pandemic in the acute care settings: a systematic review
Elshenawy, Rasha Abdelsalam; Umaru, Nkiruka; Alharbi, Amal Bandar; Aslanpour, Zoe (2023-02-10)Introduction: Antibiotics are widely administered for various indications, leading to increased antimicrobial resistance (AMR) in acute care hospitals. Since the onset of the COVID-19 pandemic, Antimicrobial Stewardship ... -
Antimicrobial Stewardship Program Implementation in a Saudi Medical City: An Exploratory Case Study.
Alghamdi, Saleh; Berrou, Ilhem; Aslanpour, Zoe; Bajnaid, Eshtyag; Hammad, Mohamed; Haseeb, Abdul; Shebl, Nada Atef (2021-03-09)Antimicrobial stewardship programs (ASPs) in hospitals have long been shown to improve antimicrobials’ use and reduce the rates of antimicrobial resistance. However, their implementation in hospitals, especially in developing ... -
Antimicrobial Stewardship Programmes in Community Healthcare Organisations in England: A Cross-Sectional Survey to Assess Implementation of Programmes and National Toolkits
Ashiru-Oredope, Diane; Doble, Anne; Akpan, Mary; Hansraj, Sejal; Shebl, Nada; Ahmad, Raheelah; Hopkins, Susan (2018-11-07)Objective: The aim of this study was to assess antimicrobial stewardship activities in Community Healthcare Organisations (CHOs) with focus on the implementation of the two national antimicrobial stewardship toolkits, ... -
Antimicrobial Stewardship Strategies, Measures and Quality Improvement During COVID-19: The Role of Pharmacist
Abdelsalam Elshenawy, Rasha; Umaru, Nikkie; Aslanpour, Zoe (2021-11-10)This research delves into Antimicrobial Stewardship (AMS) strategies and quality improvement measures in acute-care hospitals during the COVID-19 pandemic, with a focus on the role of pharmacists. It examines how the ... -
Antimicrobial Stewardship: Shorter and Longer Courses of Antibiotics in Respiratory Tract Infection Before and During the COVID-19 Pandemic at one English Foundation Trust.
Abdelsalam Elshenawy, Rasha; Umaru, Nikkie; Aslanpour, Zoe (2023-09-14)This study reveals that shorter duration of antibiotics demonstrates the same appropriateness for infections like CAP, HAP, and COPD as per local antimicrobial guidelines. Conversely, longer antibiotic durations didn't ... -
Antithrombotic in atrial fibrillation and coronary artery disease – Does less mean more?
Gue, Ying X.; Gorog, Diana; Lip, Gregory Y H (2022-06-15)In the treatment of patients with chronic coronary syndrome, the use of antiplatelets in the form of aspirin is a class 1 indication in the prevention of future thrombotic events.1 Similarly, oral anticoagulation (OAC) has ... -
Antithrombotic management during percutaneous mechanical circulatory support - defining the status quo, before agreeing quo vadis
Gorog, Diana; Combes, Alain (2024-04-30) -
Antithrombotic therapy in diabetes: Which, when, and for how long?
Ajjan, RA; Kietsiriroje, N; Badimon, L; Gorog, Diana; Angiolillo, Dominick J.; Russel, D; Rocca, Bianca; Storey, Robert F. (2021-03-25)Cardiovascular disease remains the main cause of mortality in individuals with diabetes mellitus (DM) and also results in significant morbidity. Premature and more aggressive atherosclerotic disease, coupled with an enhanced ... -
Antithrombotic therapy in patients with acute coronary syndrome complicated by cardiogenic shock or out-of-hospital cardiac arrest: a Joint Position Paper from the European Society of Cardiology (ESC) Working Group on Thrombosis, in association with the Acute Cardiovascular Care Association (ACCA) and European Association of Percutaneous Cardiovascular Interventions (EAPCI)
Gorog, Diana; Price, Susanna; Sibbing, Dirk; Baumbach, Andreas; Capodanno, Davide; Gigante, Bruna; Halvorsen, Sigrun; Huber, Kurt; Lettino, Maddalena; Leonardi, Sergio; Morais, Joao; Rubboli, Andrea; Siller-Matula, Jolanta M; Storey, Robert F.; Vranckx, Pascal; Rocca, Bianca (2020-02-12) -
Antithrombotic therapy in patients with atrial fibrillation and acute coronary syndrome
Bor, Wilbert; Gorog, Diana (2020-07-01)Abstract: Acute coronary syndrome and atrial fibrillation are both common, and can occur in the same patient. Combination therapy with dual antiplatelet therapy and oral anticoagulation increases risk of bleeding. Where ... -
Anxiety disorders : From bench to Bedside and Beyond
Starke, Jonathan; Fineberg, Naomi; Stein, Dan (Springer Nature, 2018-07-07)The anxiety disorders are prevalent, associated with high comorbidity and cause considerable disability. Despite efficacious treatment options, they are frequently misdiagnosed, and management is often suboptimal. With the ... -
Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation
Spinthakis, Nikolaos; Gue, Ying X.; Farag, Mohamed; Srinivasan, Manivannan; Wellsted, David; Lip, Gregory Y H; Arachchillage, Deepa RJ; Gorog, Diana (2019-09-01)AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which strongly relates to improved functional outcome. The impact of oral anticoagulants ... -
Application of a theoretical framework for behaviour change: Examining hospital workers real-time explanations for their non-compliance with hand hygiene guidelines
Chris, Fuller; Besser, Sarah Jane; John, McAteer; Joanne, Savage; Stone, Sheldon; Michie, Susan (2014-02-01)BACKGROUND: Insufficient use of behavioral theory to understand health care workers' (HCWs) hand hygiene compliance may result in suboptimal design of hand hygiene interventions and limit effectiveness. Previous studies ... -
Applications of artificial intelligence for benign prostatic conditions
Bansal, Saakshi; Chuluunbaatar, Yanjinlkham; Brodie, Andrew; Vasdev, Nikhil (2023-06-30)The advancement of computational abilities have taken us from the days of machines performing simple, one dimensional tasks, to themselves learning and applying knowns to unknowns. Artificial intelligence (AI) has become ... -
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency
Salek, Mir-Saeed Shayegan; Ionova, Tatyana; Johns, Jeffrey; Oliva, Esther Natalie (2018-11-19)Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, ... -
Approaches to the identification and management of depression in people living with chronic kidney disease: A scoping review of 860 papers
Pearce, Christina J.; Hall, Natalie; Hudson, Joanna L.; Farrington, Ken; Tucker, Madeleine J. Ryan; Wellsted, David; Jones, Julia; Sharma, Shivani; Norton, Sam; Ormandy, Paula; Palmer, Nick; Quinnell, Anthony; Fitzgerald, Lauren; Griffiths, Sophie; Chilcot, Joseph (2023-01-16)Background: Depression is prevalent across the spectrum of Chronic Kidney Disease and associated with poorer outcomes. There is limited evidence regarding the most effective interventions and care pathways for depression ... -
Approaches to the Study of English Forename Use
Corkery, John (2000) -
Appropriate and inappropriate influences on outpatient discharge decision making in dermatology : a prospective qualitative study
Harun, N A; Finlay, A Y; Salek, M S; Piguet, V (2015-09-01)BACKGROUND: Outpatient discharge decision making in dermatology is poorly understood. OBJECTIVE: To identify the influences on clinicians' thought processes when making discharge decisions in dermatology outpatient clinics. ... -
Are finasteride-related penile curvature/Peyronie’s disease Adverse Event Reports worthy of further clinical investigation? Disproportionality analysis based on both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) pharmacovigilance databases
Schifano, Nicolo; Cappogrosso, Paolo; Boeri, Luca; Fallara, Guiseppe; Chiappini, Stefania; Rewhorn, Matthew; Cakir, Omer Onur; Harvey, Hannah; Castiglione, Fabio; Alnajjar, Hussain; Muneer, Asif; Deho, Frederico; Schifano, Fabrizio; Montorsi, Francesco; Salonia, Andrea (2022-05-05)A limited number of studies have described patients on finasteride showing findings which were consistent with Peyronie’s disease (PD). We aimed to detect a pharmacovigilance signal of possible association between finasteride ...