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Role of the endothelium and COX-1 in prostacyclin generation by whole vessels stimulated with different agonists
Alyamanil, Malak; Kirkby, N.S.; MacKenzie, Louise Susan; Lundberg, M.H.; Warner, T.D.; Mitchell, J.A. (2012)Prostacyclin is an important cardioprotective hormone produced by the vascular wall, whose synthesis is dependent on cyclo-oxygenase (COX) enzymes. In healthy vessels the endothelium is thought to be the main site of ...