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Browsing by Author "Apergis-Schoute, Annemieke M"
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Action-Outcome Knowledge Dissociates From Behavior in Obsessive-Compulsive Disorder Following Contingency Degradation
Vaghi, Matilde M; Cardinal, Rudolf N; Apergis-Schoute, Annemieke M; Fineberg, Naomi A; Sule, Akeem; Robbins, Trevor W (2019-02-01)BACKGROUND: In obsessive-compulsive disorder (OCD), actions persist despite being inappropriate to the situation and without relationship to the overall goal. Dysfunctional beliefs have traditionally been postulated to ... -
Hyperconnectivity of the ventromedial prefrontal cortex in obsessive-compulsive disorder
Apergis-Schoute, Annemieke M; Bijleveld, Bastiaan; Gillan, Claire M.; Fineberg, Naomi; Sahakian, Barbara J. (2018-11-30)Neuroimaging research has highlighted maladaptive thalamo-cortico-striatal interactions in obsessive-compulsive disorder as well as a more general deficit in prefrontal functioning linked with compromised executive ... -
A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects
Tyagi, Himanshu; Apergis-Schoute, Annemieke M; Akram, Harith; Foltynie, Tom; Limousin, Patricia; Drummond, Lynne; Fineberg, Naomi; Matthews, Keith; Jahanshahi, Marjan; Robbins, Trevor W; Sahakian, Barbara J; Zrinco, Ludvic; Hariz, Marwan; Joyce, Eileen M (2019-05-01)Background Deep brain stimulation (DBS) is an emerging treatment for severe obsessive-compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal (VC/VS) and anteromedial subthalamic nucleus ...