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Browsing by Author "Bisson, Isabelle"
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Hedgehog Signalling in Androgen Independent Prostate Cancer
Shaw, Greg; Price, Anna M.; Ktori, Elena; Bisson, Isabelle; Purkis, Patricia E.; McFaul, Siobhan; Oliver, R. Tim D; Prowse, David M. (2008-12-01)Objectives: Androgen-deprivation therapy effectively shrinks hormone-naïve prostate cancer, both in the prostate and at sites of distant metastasis. However prolonged androgen deprivation generally results in relapse and ... -
WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics
Bisson, Isabelle; Prowse, David M. (2009-06-01)Prostate cancer cells with stem cell characteristics were identified in human prostate cancer cell lines by their ability to form from single cells self-renewing prostaspheres in non-adherent cultures. Prostaspheres exhibited ...