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Browsing by Author "Cheng, Woei Ping"
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Active Targeting
Serrano Lopez, Dolores Remedios; Lalatsa, Lalatsa (Springer Nature, 2013) -
Comb shaped amphilic polymers
Department of Pharmacy; Health & Human Sciences Research Institute; Cheng, Woei Ping (2009) -
Dilemmas in the reliable estimation of the in-vitro cell viability in magnetic nanoparticle engineering : which tests and what protocols?
Cheng, Woei Ping; Hoskins, Clare; Wang, LY; Cuschieri, A (2012)Magnetic nanoparticles [MNPs] made from iron oxides have many applications in biomedicine. Full understanding of the interactions between MNPs and mammalian cells is a critical issue for their applications. In this study, ... -
The effect of polymer architecture on the nano self-assemblies based on novel comb-shaped amphiphilic poly(allylamine)
Thompson, Colin J.; Ding, Caixia; Qu, Xiaozhong; Yang, Zhenzhong; Uchegbu, Ijeoma F.; Tetley, Laurence; Cheng, Woei Ping (2008-11)Twelve novel poly(allylamine) (PAA)-based, comb-shaped amphiphilic polymers have been developed. Hydrophobic groups of cetyl, palmitoyl and cholesteryl were randomly grafted to PAA and quaternisation was carried out on ... -
Nano self-assemblies based on cholate grafted poly-L-lysine enhanced the solubility of sterol-like drugs
Gu, Jingxia; Cheng, Woei Ping; Hoskins, Clare; Lin, Paul Kong Thoo; Zhao, Lingling; Zhu, Lijun; Qu, Xiaozhong; Yang, Zhenzhong (2011)The physicochemical compatibility between amphiphilic polymers and hydrophobic drugs has been recognized as an important issue for improving the drug solubilisation in polymeric micelle formulations. In this work, poly-L-lysine ... -
Novel fluorescent amphiphilic poly(allylamine) and their supramacromolecular self-assemblies in aqueous media.
Cheng, Woei Ping; Hoskins, Clare; Paul, Kong Thoo-Lin; Tetley, Laurence (2012)Fluorescent amphiphilic polymers were produced by grafting different types and levels of hydrophobic pendant groups with intrinsic fluorescent properties (fluorenylmethoxy carbonyl (Fmoc), dimethylamino-1-naphthalenesulfonyl ... -
Peptides, Proteins and Antibodies
Lalatsa, Lalatsa (Springer Nature, 2013)Peptide and protein therapeutics are increasingly able to address a growing range of clinical pathologies and their high specificity and potency combined with low toxicity of metabolic products and minimal potential for ... -
pH-triggered reversible "stealth" polycationic micelles
Gu, Jingxia; Cheng, Woei Ping; Liu, Jiguang; Lo, Sum-Yee; Smith, David; Qu, Xiaozhong; Yang, Zhenzhong (2008-01)Amphiphilic polycations with a "stealth" cationic nature have been designed and synthesized by the PEGylation of polycationic amphiphile via a novel pH responsible benzoic imine linker. The linkage is stable in aqueous ... -
Polymeric Nanoparticles
Uchegbu, I.F.; Lalatsa, Lalatsa; Wong, Dennis (Springer Nature, 2013)Self-assembling polymers, which are either amphiphilic block copolymers with hydrophobic and hydrophilic blocks, hydrophilic polymer backbones substituted with hydrophobic units or polymers with a low aqueous solubility, ... -
The Use of Nano Polymeric Self-Assemblies Based on Novel Amphiphilic Polymers for Oral Hydrophobic Drug Delivery
Cheng, Woei Ping; Hoskins, Clare; Paul, Kong Thoo-Lin; Tetley, Laurence (2012)To investigate the use of nano self-assemblies formed by polyallylamine (PAA) modified with 5 or 10% mole fluorenylmethoxy carbonyl (Fmoc5/10), dimethylamino-1-naphthalenesulfonyl (Dansyl5/10) and 5% mole cholesteryl group ...