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The effect of aerodynamic particle size and solid state disorder on salmeterol xinafoate deposition from pressurised metered dose and dry powder inhaler formulations
Jaffari, S.; Sandhu, G.; Martin, G. P.; Forbes, B.; Collins, E.; Murnane, D. (2013-08)The production of active pharmaceutical ingredients (APIs) generally consists of crystallisation followed by a comminution process which provides limited control over particle size and energises particle surfaces. Both ...