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Completion of the sequence of the Aspergillus fumigatus partitivirus 1 genome.
Filippou, Charalampos; Coutts, Robert; Stevens, David A.; Sabino, Raquel; Kotta Loizou, Ioli (2020-05-27)A Portuguese isolate of Aspergillus fumigatus was found to contain three double-stranded (ds) RNA elements ranging in size from 1.1 to 1.8 kbp and comprising the genome of a strain of Aspergillus fumigatus partitivirus 1 ... -
Development of a novel approach of attenuating fungal disease in pine trees
Kotta-Loizou, Loly; Coutts, Robert (2022) -
Expression and clinical significance of concomitant FAK/SRC and p-Paxillin in mobile tongue squamous cell carcinoma.
Theocharis, Stamatios; Kotta-Loizou, Ioly; Giaginis, Constantinos; Alexandrou, Paraskevi; Danas, Eugene; Tsourouflis, Gerasimos; Tsoukalas, Nikolaos; Coutts, Robert; Tasoulas, Jason; Klijanienko, Jeremy (2017-03-01)BACKGROUND/AIM: The focal adhesion kinase (FAK)/SRC phosphorylation cascade and its downstream target paxillin have been implicated in malignant transformation, tumor growth and progression, together with metastasis. The ... -
ICTV Virus Taxonomy Profile: Chrysoviridae
Kotta Loizou, Ioly; Castón, José R.; Coutts, Robert; Hillman, Bradley I.; Jiang, Daohong; Kim, Dae-Hyuk; Moriyama, Hiromitsu; Suzuki, Nobuhiro; ICTV Report Consortium (2020-01-20)Members of the family Chrysoviridae are isometric, non-enveloped viruses with segmented, linear, dsRNA genomes. There are 3–7 genomic segments, each of which is individually encapsidated. Chrysoviruses infect fungi, plants ... -
ICTV Virus Taxonomy Profile: Polymycoviridae 2022
Kotta Loizou, Ioly; Coutts, Robert; ICTV Report Consortium (2022-05-31)Members of the family Polymycoviridae are small viruses with multi-segmented and non-conventionally encapsidated double-stranded (ds) RNA genomes. Typically, polymycoviruses have four genomic segments, although some have ... -
Identification, Molecular Characterization, and Biology of a Novel Quadrivirus Infecting the Phytopathogenic Fungus Leptosphaeria biglobosa.
Shah, Unnati; Fitt, Bruce; Kotta-Loizou, Ioly; Coutts, Robert (2018-12-25)Here we report the molecular characterisation of a novel dsRNA virus isolated from the filamentous, plant pathogenic fungus Leptosphaeria biglobosa and known to cause significant alterations to fungal pigmentation and ... -
Multiplex Detection of Aspergillus fumigatus Mycoviruses.
Ozkan, S.,; Coutts, Robert (2018-05-08)Mycoviruses are viruses that naturally infect and replicate in fungi. They are widespread in all major fungal groups including plant and animal pathogenic fungi. Several dsRNA mycoviruses have been reported in Aspergillus ... -
Mycoviral Population Dynamics in Spanish Isolates of the Entomopathogenic Fungus Beauveria bassiana
Filippou, Charalampos; Garrido-Jurado, Inmaculada; Meyling, Nicolai V.; Quesada-Moraga, Enrique; Coutts, Robert; Kotta-Loizou, Ioly (2018-11-24)The use of mycoviruses to manipulate the virulence of entomopathogenic fungi employed as biocontrol agents may lead to the development of novel methods to control attacks by insect pests. Such approaches are urgently ... -
Mycovirus induced hypervirulence of Leptosphaeria biglobosa enhances systemic acquired resistance to Leptosphaeria maculans in Brassica napus
Shah, Unnati; Kotta-Loizou, Ioly; Fitt, Bruce; Coutts, Robert (2019-11-20)Phoma stem canker (blackleg) is one of the most important diseases of winter oilseed rape (Brassica napus) world-wide and is caused by a complex that comprises at least two species: Leptosphaeria maculans and Leptosphaeria ... -
The polymycovirus-mediated growth enhancement of the entomopathogenic fungus Beauveria bassiana is dependent on carbon and nitrogen metabolism
Filippou, Charalampos; Diss, Rebecca Maria; Daudu, John Oluwayemi; Coutts, Robert; Kotta Loizou, Ioli (2021-02-02)Polymycoviridae is a growing family of mycoviruses whose members typically have non-conventional capsids and multi-segmented, double-stranded (ds) RNA genomes. Beauveria bassiana polymycovirus (BbPmV) 1 is known to enhance ... -
Studies on the virome of the entomopathogenic fungus Beauveria bassiana reveal novel dsRNA elements and mild hypervirulence.
Kotta-Loizou, Ioly; Coutts, Robert (2017-01-23)The entomopathogenic fungus Beauveria bassiana has a wide host range and is used as a biocontrol agent against arthropod pests. Mycoviruses have been described in phytopathogenic fungi while in entomopathogenic fungi their ... -
Virus Infection of Aspergillus fumigatus Compromises the Fungus in Intermicrobial Competition
Nazik, Hasan; Kotta Loizou, Ioly; Sass, Gabriele; Coutts, Robert; Stevens, David (2021-04-16)Aspergillus and Pseudomonas compete in nature, and are the commonest bacterial and fungal pathogens in some clinical settings, such as the cystic fibrosis lung. Virus infections of fungi occur naturally. Effects on fungal ...