Browsing by Author "Cox, Helen"

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    • Dysregulation of epithelial ion transport and neurochemical changes in the colon of a parkinsonian primate 

      Coletto, Erika; Tough, Ian; Pritchard, Sara; Hikima, Atsuko; Jackson, Michael; Jenner, Peter; Chaudhuri, K. Ray; Cox, Helen; Iravani, Mahmoud; Rose, Sarah (2021-01-21)
      The pathological changes underlying gastrointestinal (GI) dysfunction in Parkinson’s disease (PD) are poorly understood and the symptoms remain inadequately treated. In this study we compared the functional and neurochemical ...

    • Physiological and Functional Changes in the Colon of MPTP-Treated Common Marmosets 

      Coletto, Erika; Tough, Ian; Hikima, Atsuko; Iravani, Mahmoud M.; Chaudhuri, K. Ray; Jenner, Peter; Cox, Helen; Rose, Sarah (2014-05)
      Objective: To determine changes in colon pathophysiology in MPTP-treated common marmosets. Background: Constipation is a common premotor symptom of Parkinson's disease (PD) and may be the result of changes in colonic ...