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Browsing by Author "Dass, B."
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Behavioural and immunohistochemical changes following supranigral administration of sonic hedgehog in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets
Dass, B.; Iravani, Mahmoud M.; Jackson, M. J.; Engber, T. M.; Galdes, A.; Jenner, P. (2002)Sonic hedgehog (SHH) has trophic actions on dopaminergic cell cultures and protects them from MPP+ toxicity but its in vivo actions have not been explored. We now investigate the effects of unilateral supranigral administration ... -
Sonic hedgehog delivered by an adeno-associated virus protects dopaminergic neurones against 6-OHDA toxicity in the rat
Dass, B.; Iravani, Mahmoud M.; Huang, C.; Barsoum, J.; Engber, T. M.; Galdes, A.; Jenner, P. (2005-06)Direct intracerebral administration of sonic hedgehog (SHH) reduces 6-OHDA and MPTP toxicity to nigral dopaminergic cells in rats and primates. To determine whether transfection of the DNA sequence for SHH using viral ...