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Browsing by Author "Drakulic, Branko J."
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The Effect of Phenyl Substituents on C-13 NMR Shifts and Metal Ions Binding to 4-Phenyl-2,4-Dioxobutanoic Acid Derivatives
Verbic, Tatjana Z.; Drakulic, Branko J.; Zloh, Mire; Juranic, Ivan O. (2008-12)Butanoic moiety of 4-aryl-2,4-dioxobutanoic acids is involved in interactions with metal ions within HIV-1 integrase active site. Sixteen congeneric 4-phenyl-2,4-dioxobutanoic acid derivatives with different substitution ... -
Tautomerism of 4-phenyl-2,4-dioxobutanoic acid. Insights from pH ramping NMR study and quantum chemical calculations
Cvijetic, Ilija; Pesic, Milos P.; Todorov, Miljana D.; Juranic, Ivan O.; Drakulic, Branko J.; Verbic, Tatjana; Zloh, Mire (2017-09-30)Aryldiketo acids (ADKs) exhibit the variety of biological activities, mainly due to large affinity toward divalent metal ions. Metal complexation ability of ADKs, as well as interactions with proteins, depend on tautomeric ...