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Comparison of pepsinogen forms in cattle, sheep and goats
Mostofa, M.; McKellar, Quintin; Eckersall, P. D. (1990)Different types and subtypes of pepsinogen extracted from bovine, ovine and caprine abomasa were found to differ according to their phosphate content and relative molecular mass (Mr). Bovine pepsinogens had organic phosphate ... -
Effect of Ostertagia ostertagi secretions and various putative secretagogues and inhibitors on aminopyrine accumulation in dispersed bovine abomasal gland cells
McKellar, Quintin; Mostofa, M.; Eckersall, P. D. (1990)Aminopyrine accumulation in suspensions of isolated gastric glands was used to determine the effect of Ostertagia ostertagi secretions and putative secretagogues and inhibitors on abomasal parietal cells. Parasite secretions ... -
Forms of bovine pepsinogen in plasma from cattle with three different 'syndromes' of Ostertagia ostertagi infection
McKellar, Quintin; Eckersall, P. D.; Duncan, J. L.; Armour, J. (1988-01)Calves infected orally with third stage larvae of Ostertagia ostertagi or infected with adult O ostertagi by direct transplantation into the abomasum had raised plasma pepsinogen activity, as did four-year-old dairy cattle ... -
Immunological studies of bovine pepsinogen and problems in the development of an Elisa for Ostertagiasis
Mostofa, M.; McKellar, Quintin; Eckersall, P. D. (1995) -
Isometamidium in pigs : disposition kinetics, tissue residues and adverse reactions
Kinabo, L. D.; McKellar, Quintin; Eckersall, P. D. (1991-01)The disposition and adverse effects of the anti-trypanosomal drug isometamidium in pigs were evaluated. Following intramuscular administration of the drug at doses of 0.5, 15 and 35 mg kg-1, the drug was rapidly absorbed ... -
Multiple forms of bovine pepsinogen : isolation and identification in serum from calves with ostertagiasis
Eckersall, P. D.; Macaskill, J.; McKellar, Quintin; Bryce, K. L. (1987-11)By using fast protein liquid chromatography (FPLC) a new form of bovine pepsinogen has been identified. Compared with the previously isolated pepsinogen (PG I) the new pepsinogen (PG II) is less mobile on agarose ... -
Pepsinogen types in worm-free sheep and in sheep infected with Ostertagia circumcincta and Haemonchus contortus
Mostofa, M.; McKellar, Quintin; Eckersall, P. D.; Gray, D. (1990)Pepsinogen isolated from the plasma of Dorset wethers with abomasal burdens of Ostertagia circumcincta was found to have the same proportions of three zymogen subtypes as that isolated from the plasma of Merino wethers ... -
Stimulated pepsinogen secretion from dispersed abomasal glands exposed to Ostertagia species secretion
McKellar, Quintin; Mostofa, M.; Eckersall, P. D. (1990)Carbachol and secretions from Ostertagia species parasites significantly (P less than 0.001) stimulated isolated preparations of dispersed gastric glands from bovine and ovine abomasal mucosa to secrete pepsinogen. Atropine ...