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Browsing by Author "Eric, Slavica"
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Insights into mechanism of anticancer activity of pentacyclic oxindole alkaloids of Uncaria tomentosa by means of a computational reverse virtual screening and molecular docking approach
Kozielewicz, Pawel; Paradowska, Katarzyna; Eric, Slavica; Wawer, Iwona; Zloh, Mire (2014-07-01)Alkaloid-rich extract from Uncaria tomentosa (eng. Cat’s claw) has been reported to cause apoptosis in vitro in cancer lines. Oxindole pentacyclic alkaloids of the plant are responsible for this effect, yet their biological ... -
Study of the selectivity of alpha(1)-adrenergic antagonists by molecular modeling of alpha(1a)-, alpha(1b)-, and alpha(1d)-adrenergic receptor subtypes and docking simulations
Eric, Slavica; Solmajer, Tom; Kotnik, Miha; Zloh, Mire; Agbaba, Danica (2013-06)Modeling of alpha(1a), alpha(1b), and alpha(1d) adrenergic receptor subtypes has been performed using InsightII software and bovine rhodopsin as a template. Adrenaline and noradrenaline, as endogenous agonists, were docked ...