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Browsing by Author "Etifa, Perezimor"
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The Efficacy of Probiotics in Modulating Clostridium difficile Spore Germination, Growth and Toxin Production in an in vitro Human Gut Model
Etifa, Perezimor (2021-01-22)Background and aims Clostridium difficile infection (CDI) remains a healthcare burden and recurrent CDI (rCDI) still affects 20-30% of patients. Probiotics are live microorganisms that confer a host health benefit, but ... -
Non-Toxigenic Clostridioides difficile Strain E4 (NTCD-E4) Prevents Establishment of Primary C. difficile Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model
Etifa, Perezimor; Rodríguez, César; Harmanus, Céline; Sanders, Ingrid M. J. G.; Sidorov, Igor A.; Mohammed, Olufunmilayo A.; Savage, Emily; Timms, Andrew R.; Freeman, Jane; Smits, Wiep Klaas; Wilcox, Mark H.; Baines, Simon D. (2023-02-22)Clostridioides difficile infection (CDI) remains a significant healthcare burden. Non-toxigenic C. difficile (NTCD) strains have shown a benefit in preventing porcine enteritis and in human recurrent CDI. In this study, ...