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The validation of an invitro colonic motility assay as a biomarker for gastrointestinal adverse drug reactions
Keating, Christopher; Ewart, Lornal; Gibbons, Stephen; Grundy, Luke; Valentin, Jean-Pierre; Grundy, David (2010-06)Motility-related gastrointestinal adverse drug reactions (GADRs), such as constipation and diarrhea, are some of the most frequently reported adverse events associated with the clinical development of new chemical entities, ...