Now showing items 1-2 of 2

    • Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study 

      Chandrasekaran, Dhivya; Sobocan, Monika; Blyuss, Oleg; Miller, Rowan E.; Evans, Olivia; Crusz, Shanthini M.; Mills-Baldock, Tina; Sun, Li; Hammond, Rory F. L.; Gaba, Faiza; Jenkins, Lucy A.; Ahmed, Munaza; Kumar, Ajith; Jeyarajah, Arjun; Lawrence, Alexandra C.; Brockbank, Elly; Phadnis, Saurabh; Quigley, Mary; El Khouly, Fatima; Wuntakal, Rekha; Faruqi, Asma; Trevisan, Giorgia; Casey, Laura; Burghel, George J.; Schlecht, Helene; Bulman, Michael; Smith, Philip; Bowers, Naomi L.; Legood, Rosa; Lockley, Michelle; Wallace, Andrew; Singh, Naveena; Evans, D. Gareth; Manchanda, Ranjit (2021-08-27)
      We present findings of a cancer multidisciplinary-team (MDT) coordinated mainstreaming pathway of unselected 5-panel germline BRCA1/BRCA2/RAD51C/RAD51D/BRIP1 and parallel somatic BRCA1/BRCA2 testing in all women with ...
    • Population Study of Ovarian Cancer Risk Prediction for Targeted Screening and Prevention 

      Gaba, Faiza; Blyuss, Oleg; Liu, Xinting; Goyal, Shivam; Lahoti, Nishant; Chandrasekaran, Dhivya; Kurzer, Margarida; Kalsi, Jatinderpal; Sanderson, Saskia; Lanceley, Anne; Ahmed, Munaza; Side, Lucy; Gentry-Maharaj, Aleksandra; Wallis, Yvonne; Wallace, Andrew; Waller, Jo; Luccarini, Craig; Yang, Xin; Dennis, Joe; Dunning, Alison; Lee, Andrew; Antoniou, Antonis C; Legood, Rosa; Menon, Usha; Jacobs, Ian; Manchanda, Ranjit (2020-05-15)
      Unselected population-based personalised ovarian cancer (OC) risk assessment combining genetic/epidemiology/hormonal data has not previously been undertaken. We aimed to perform a feasibility study of OC risk stratification ...