Now showing items 1-2 of 2

    • Current detection rates and time-to-detection of all identifiable BRCA carriers in the Greater London population 

      Manchanda, Ranjit; Blyuss, Oleg; Gaba, Faiza; Gordeev, Vladimir Sergeevich; Jacobs, Chris; Burnell, Matthew; Gan, Carmen; Taylor, Rohan; Turnbull, Clare; Legood, Rosa; Zaikin, Alexey; Antoniou, Antonis C; Menon, Usha; Jacobs, Ian (2018-04-05)
      BACKGROUND: BRCA carrier identification offers opportunities for early diagnoses, targeted treatment and cancer prevention. We evaluate BRCA- carrier detection rates in general and Ashkenazi Jewish (AJ) populations across ...
    • Population Study of Ovarian Cancer Risk Prediction for Targeted Screening and Prevention 

      Gaba, Faiza; Blyuss, Oleg; Liu, Xinting; Goyal, Shivam; Lahoti, Nishant; Chandrasekaran, Dhivya; Kurzer, Margarida; Kalsi, Jatinderpal; Sanderson, Saskia; Lanceley, Anne; Ahmed, Munaza; Side, Lucy; Gentry-Maharaj, Aleksandra; Wallis, Yvonne; Wallace, Andrew; Waller, Jo; Luccarini, Craig; Yang, Xin; Dennis, Joe; Dunning, Alison; Lee, Andrew; Antoniou, Antonis C; Legood, Rosa; Menon, Usha; Jacobs, Ian; Manchanda, Ranjit (2020-05-15)
      Unselected population-based personalised ovarian cancer (OC) risk assessment combining genetic/epidemiology/hormonal data has not previously been undertaken. We aimed to perform a feasibility study of OC risk stratification ...