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Browsing by Author "Glynn, Macdara T."
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Digital process control of multi-step assays on centrifugal platforms using high-low-high rotational-pulse triggered valving
Early, Philip L.; Kilcawley, Niamh A.; McArdle, Niamh A.; Renou, Marine; Kearney, Sinéad M.; Mishra, Rohit; Dimov, Nikolay; Glynn, Macdara T.; Ducrée, Jens; Kinahan, David J. (2023-09-08)Due to their capability for comprehensive sample-to-answer automation, the interest in centrifugal microfluidic systems has greatly increased in industry and academia over the last quarter century. The main applications ... -
Event-triggered logical flow control for comprehensive process integration of multi-step assays on centrifugal microfluidic platforms
Kinahan, David J.; Kearney, Sinéad M.; Dimov, Nikolay; Glynn, Macdara T.; Ducrée, Jens (2014-07-07)The centrifugal "lab-on-a-disc" concept has proven to have great potential for process integration of bioanalytical assays, in particular where ease-of-use, ruggedness, portability, fast turn-around time and cost efficiency ... -
Paper imbibition for timing of multi-step liquid handling protocols on event-triggered centrifugal microfluidic lab-on-a-disc platforms
Kinahan, David J.; Kearney, Sinéad M.; Faneuil, Olivier P.; Glynn, Macdara T.; Dimov, Nikolay; Ducrée, Jens (2015)Rotational microfluidic platforms have attracted swiftly growing interest over the last decade due to their suitability for integration and automation of sample preparation and detection. Valving is of pivotal importance ... -
Solvent-selective routing for centrifugally automated solid-phase purification of RNA
Dimov, Nikolay; Clancy, Eoin; Gaughran, Jennifer; Boyle, David; Mc Auley, Darren; Glynn, Macdara T.; Dwyer, Róisín M.; Coughlan, Helena; Barry, Thomas; Barrett, Louise M.; Smith, Terry J.; Ducrée, Jens (2015-05-01)We present a disc-based module for rotationally controlled solid-phase purification of RNA from cell lysate. To this end, multi-stage routing of a sequence of aqueous and organic liquids into designated waste and elution ...