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Browsing by Author "Gokbulut, C."
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Comparative plasma disposition of fenbendazole, oxfendazole and albendazole in dogs
Gokbulut, C.; Bilgili, A.; Hanedan, B.; McKellar, Quintin (2007)The plasma disposition of fenbendazole (FBZ), oxfendazole (OFZ) and albendazole (ABZ); and the enantiospecific disposition of OFZ, and ABZSO produced were investigated following an oral administration (50 mg/kg) in dogs. ... -
Comparative plasma disposition, bioavailability and efficacy of ivermectin following oral and pour-on administrations in horses
Gokbulut, C.; Cirak, V. Y.; Senlik, B.; Aksit, D.; Durmaz, M.; McKellar, Quintin (2010)Pour-on formulations of endectocides decrease the risk of injury for both user and animal, and are particularly convenient for animal owners who can apply the product. This study was designed to investigate the plasma ... -
Comparative plasma dispositions of ivermectin and doramectin following subcutaneous and oral administration in dogs
Gokbulut, C.; Karademir, U.; Boyacioglu, M.; McKellar, Quintin (2006)This study evaluates the comparative plasma dispositions of ivermectin (IVM) and doramectin (DRM) following oral and subcutaneous administration (200 μg/kg) over a 40-day period in dogs. Twenty bitches were allocated by ... -
The effect of sesame and sunflower oils on the plasma disposition of ivermectin in goats
Gokbulut, C.; Karademir, U.; Boyacioglu, M.; McKellar, Quintin (2008)The effect of sesame oil (SSO) and sunflower oil (SFO) (the excipients) on the plasma disposition of ivermectin (IVM) following intravenous (i.v.) and subcutaneous (s.c.) administration at a dosage of 200 μg/kg was ... -
The effects of different ages and dosages on the plasma disposition and hair concentration profile of ivermectin following pour-on administration in goats
Gokbulut, C.; Cirak, V. Y.; Senlik, B.; Aksit, D.; McKellar, Quintin (2011)The effects of different ages and dosages on the plasma disposition and hair degradation of ivermectin (IVM) were investigated following pour-on administration in goats. Twenty-eight female Saanen goats allocated into two ... -
Fenbendazole pharmacokinetics, metabolism, and potentiation in horses
McKellar, Quintin; Gokbulut, C.; Muzandu, K.; Benchaoui, H. (2002-11)The present study was designed to describe the pharmacokinetics and fecal excretion of fenbendazole (FBZ) and fenbendazole sulphoxide (FBZSO) and their metabolites in horses, to investigate the effects which concurrent ... -
Pharmacokinetic disposition and faecal excretion of pyrantel embonate following oral administration in horses
Gokbulut, C.; Nolan, A.M.; McKellar, Quintin (2001-02) -
Pharmacological assessment of netobimin as a potential anthelmintic for use in horses : Plasma disposition, faecal excretion and efficacy
Gokbulut, C.; Cirak, V. Y.; Senlik, B.; Yildirim, F.; McKellar, Quintin (2009)This study aimed to determine the plasma disposition and faecal excretion of netobimin (NTB) and its respective metabolites as well as the efficacy against strongyles in horses following oral administration. Netobimin (10 ... -
Plasma disposition and faecal excretion of oxfendazole, fenbendazole and albendazole following oral administration to donkeys
Gokbulut, C.; Akar, F.; McKellar, Quintin (2006)Fenbendazole (FBZ), oxfendazole (fenbendazole sulphoxide, FBZSO), and albendazole (ABZ) were administered orally to donkeys at 10 mg/kg bodyweight. Blood and faecal samples were collected from 1 to 120 h post-treatment. ... -
Plasma disposition, faecal excretion and in vitro metabolism of oxibendazole following oral administration in horses
Gokbulut, C.; Nolan, A.M.; McKellar, Quintin (2002-02)Oxibendazole (OBZ) was administered to eight horses at an oral dose of 10 mg kg(-1) bodyweight each. Parent OBZ could only be detected in plasma at the 0.5 and 1.0 hours post administration sampling times and the mean ... -
Plasma pharmacokinetics and faecal excretion of ivermectin, doramectin and moxidectin following oral administration in horses
Gokbulut, C.; Nolan, A.M.; McKellar, Quinton (2001-09)The present study was carried out to investigate whether the pharmacokinetics of avermectins or a milbemycin could explain their known or predicted efficacy in the horse. The avermectins, ivermectin (IVM) and doramectin ...