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Browsing by Author "Howard, Philip W."
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Solution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct : molecular basis for unexpectedly high DNA helix stabilization
Antonow, Dyeison; Barata, Teresa; Jenkins, Terence C.; Parkinson, Gary N.; Howard, Philip W.; Thurston, David E; Zloh, Mire (2008)The naturally occurring pyrrolo[2,1- c][1,4]benzodiazepine (PBD) monomers such as sibiromycin, anthramycin, and tomaymycin form stable covalent adducts with duplex DNA at purine-guanine-purine sites. A correlative relationship ...