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    • C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins 

      Anderson, Edward N.; Corkins, Mark E.; Li, Jia Cheng; Singh, Komudi; Parsons, Sadé; Tucey, Tim M.; Sorkaç, Altar; Huang, Huiyan; Dimitriadi, Maria; Sinclair, David A.; Hart, Anne C. (2016-03-01)
      Moderate stress can increase lifespan by hormesis, a beneficial low-level induction of stress response pathways. 5'-fluorodeoxyuridine (FUdR) is commonly used to sterilize Caenorhabditis elegans in aging experiments. ...