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Browsing by Author "Isaacs, Adrian M."
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C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
Fratta, Pietro; Mizielinska, Sarah; Nicoll, Andrew J; Zloh, Mire; Fisher, Elizabeth M. C.; Parkinson, Gary; Isaacs, Adrian M. (2012)Large expansions of a non-coding GGGGCC-repeat in the first intron of the C9orf72 gene are a common cause of both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). G-rich sequences have a propensity ...