Browsing by Author "Jones, A. B."

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    • NK1 antagonists based on seven membered lactam scaffolds 

      Elliott, J. M.; Carlson, E. J.; Chcchi, G. G.; Dirat, O.; Dominguez, M.; Gerhard, U.; Jelley, R.; Jones, A. B.; Kurtz, M. M.; Tsao, K. I.; Wheeldon, A. (2006-06-01)
      A new class of high affinity hNK(1)R antagonists based on seven-membered ring cores has been identified. This series, with relatively simple, compact structures, includes compounds with high affinity, good selectivity, and ...