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Hypoactivation and Dysconnectivity of a Frontostriatal Circuit During Goal-Directed Planning as an Endophenotype for Obsessive-Compulsive Disorder
Vaghi, Matilde M.; Hampshire, Adam; Kaser, Muzaffer; Fineberg, Naomi; Brühl, Annette B.; Sahakian, Barbara J.; Chamberlain, Samuel R.; Robbins, Trevor W. (2017-11-01)Background The symptoms of obsessive-compulsive disorder (OCD) have been postulated to result from impaired executive functioning and excessive habit formation at the expense of goal-directed control and have been objectively ...