- UHRA Home
- Browsing by Author
Browsing by Author "Liao, Y. H."
Now showing items 1-5 of 5
-
The effects of polyvinyl alcohol on the in vitro stability and delivery of spray-dried protein particles from surfactant-free HFA 134a-based pressurised metered dose inhalers
Liao, Y. H.; Jones, Stuart A.; Nazir, T.; Martin, Gary P.; Brown, Marc (2005-11-04)The objective of the present study was to investigate the physical stability of spray-dried proteins within surfactant-free hydrofluoroalkane (HFA) pressurised metered dose inhalers (pMDIs) during prolonged storage. Two ... -
Hyaluronan: Pharmaceutical characterization and drug delivery
Liao, Y. H.; Jones, Stuart A.; Forbes, B.; Martin, Gary P.; Brown, Marc (2005)Hyaluronic acid ( HA), is a polyanionic polysaccharide that consists of N-acetyl-D-glucosamine and beta-glucoronic acid. It is most frequently referred to as hyaluronan because it exists in vivo as a polyanion and not in ... -
Investigation of the physical properties of spray-dried stabilised lysozyme particles
Liao, Y. H.; Brown, Marc; Quader, A.; Martin, Gary P. (2003-09)The aim of this study was to investigate the effect of the composition of formulations on the physical properties, including glass-transition temperatures (Tg) and aerodynamic-related characteristics, of spray-dried lysozyme ... -
Investigation of the stabilisation of freeze-dried lysozyme and the physical properties of the formulations
Liao, Y. H.; Martin, Gary P.; Brown, Marc (2004-07)The long-term stability of a protein formulation requires that the glass transition temperature (T-g) of the formulation should be maximised and the perturbation of the protein native structure in the dried form after ... -
Turbidimetric and HPLC assays for the determination of formulated lysozyme activity
Liao, Y. H.; Brown, Marc; Martin, Gary P. (2001-04)In several studies lysozyme has been employed as a model protein to investigate the effects of formulation factors upon biological activity. The aim of this work was to develop and validate an HPLC technique to assay ...