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Browsing by Author "Lim, S. T."
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In vivo evaluation of novel hyaluronan/chitosan microparticulate delivery systems for the nasal delivery of gentamicin in rabbits
Lim, S. T.; Forbes, B.; Berry, D. J.; Martin, Gary P.; Brown, Marc (2002-01)Biodegradable microparticles containing gentamicin were prepared using chitosan hydroglutamate (CH), hyaluronic acid (HA) and a combination Of both polymers by a solvent evaporation method. These formulations were administered ... -
Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan
Lim, S. T.; Martin, Gary P.; Berry, D. J.; Brown, Marc (2000-05-15)Rapid mucociliary clearance of intranasally administered drugs is often a key factor in determining the bioavailability of such therapeutic agents. The use of mucoadhesive microparticles provide a potential strategy for ...