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Low-Impact Ampakine CX1739 Exerts Pro-Cognitive Effects and Reverses Opiate-Induced Respiratory Depression in Rodents
Radin, Daniel Pierce; Zhong, Sheng; Cerne, Rok; Shoaib, Mohammed; Witkin, Jeffrey M.; Lippa, Arnold (2024-02-26)AMPA-glutamate receptors (AMPARs) are expressed throughout the CNS and mediate the majority of fast excitatory synaptic transmission. Ampakines are orally available small molecules that bind allosterically to AMPARs and ...