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Browsing by Author "Loi, Barbara"
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4,4’-dimethylaminorex (‘4,4’-DMAR’; ‘Serotoni’) misuse; a web-based study
Loi, Barbara; Zloh, Mire; Antonietta, Maria; Corkery, John; Schifano, Fabrizio (2017-06-28)Background: 4,4′-DMAR (4,4’-dimethylaminorex; ‘Serotoni’) is a potent stimulant drug which has recently been associated with a number of fatalities in Europe. Over the last few years, online communities have emerged as ... -
Deaths in the Lesbian, Gay, Bisexual and Transgender United Kingdom communities associated with GHB and precursors
Corkery, John M; Loi, Barbara; Claridge, Hugh; Goodair, Christine; Schifano, Fabrizio (2017-11-08)Background Misuse of gammahydroxybutrate (GHB) and its prodrugs gammabutyrolactone (GBL) and 1,4 butanediol (1,4-BD) has increased greatly since the early 1990s, particularly amongst lesbian, gay, bisexual and transgender ... -
Deaths of individuals aged 16-24 years in the UK after using mephedrone
Loi, Barbara; Corkery, John; Claridge, Hugh; Goodair, Christine; Chiappini, Stephania; Gimeno Clemente, Carla; Schifano, Fabrizio (2015-07-28)Objective: Mephedrone is a stimulant drug chemically related to amphetamine, with effects similar to those of amphetamine and cocaine. This study aims to analyse fatalities following ingestion of mephedrone in the UK amongst ... -
Drug-related deaths in the UK: January-December 2012 : Annual report 2013
Corkery, John; Claridge, Hugh; Loi, Barbara; Goodair, Christine; Schifano, Fabrizio (International Centre for Drug Policy, 2014-02-12)Drug-related deaths reported by Coroners in England, Wales, Northern Ireland, Guernsey, Jersey and the Isle of Man; Police forces in Scotland; & the Northern Ireland Statistics and Research Agency -
The evolution and characteristics of UK deaths involving GHB and its analogues
Corkery, John; Loi, Barbara; Claridge, Hugh; Goodair, Christine; Corazza, Ornella; Elliott, Simon; Schifano, Fabrizio (2014-03)Introduction: misuse of gamma hydroxybutyrate (GHB) and gamma butyrolactone (GBL) increased in Western countries from the early 1990s. The period since has seen a rising numbers of deaths. This presentation outlines the ... -
Fatalities Associated with Mephedrone in Combination with Other Stimulant Drugs in Young People Aged 16-24 Years
Loi, Barbara; Chiappini, Stephania; Claridge, Hugh; Corkery, John; Gimeno Clemente, Carla; Goodair, Christine; Schifano, Fabrizio (2013-12)Introduction: Mephedrone is a stimulant Class B drug chemically related to amphetamine. It comes in tablet or powder form and has no therapeutic use. Mephedrone’s reported effects are similar to those of amphetamine and ... -
Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4 butanediol (1,4-BD; BDO) : a literature review with a focus on UK fatalities related to non-medical use
Corkery, John; Loi, Barbara; Claridge, Hugh; Goodair, Christine; Corazza, Ornella; Elliott, Simon; Schifano, Fabrizio (2015-06)Misuse of gamma hydroxybutrate (GHB) and gamma butyrolactone (GBL) has increased greatly since the early 1990s, being implicated in a rising number of deaths. This paper reviews knowledge on GHB and derivatives, and explores ... -
Methoxetamine-related deaths in the UK : an overview
Chiappini, Stephania; Claridge, Hugh; Corkery, John; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2015-07-28)Objective: The goal of this study is to provide an update on the data given on methoxetamine (MXE)-related fatalities that occurred in 2011–2013, presented at the Second International Conference on Novel Psychoactive ... -
Methoxetamine: An Analogue of Ketamine
Chiappini, Stephania; Claridge, Hugh; Corkery, John; Gimeno Clemente, Carla; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2013-12)Introduction: Methoxetamine acts similarly to a non-competitive antagonist at the N-methyl-aspartate receptor and a Dopamine reuptake inhibitor. Its behavioural effects resemble those induced by dissociative anesthetics, ... -
Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids : BB-22, 5F-PB-22, 5F-AKB-48 and STS-135
De Luca, Maria Antonietta; Castelli, M. Paola; Loi, Barbara; Porcu, Alessandra; Martorelli, Mariella; Miliano, Cristina; Kellett, Kathryn; Davidson, Colin; Stair, Jacqueline L.; Schifano, Fabrizio; Di Chiara, Gaetano (2016-06-01)In order to investigate the in vivo dopamine (DA) stimulant properties of selected 3rd generation Spice/K2 cannabinoids, BB-22, 5F-PB-22, 5F-AKB-48 and STS-135, their in vitro affinity and agonist potency at native rat and ... -
Neurochemical and Neuropharmacological Studies on a Range of Novel Psychoactive Substances
Loi, Barbara (2018-06-15)Introduction: Over recent decades, there has been an increase in the availability and use of Novel Psychoactive Substances (NPS) all over the world. They include several classes of chemicals that mimic the effects of illicit ... -
‘Special M’ related fatalities in the UK.
Chiappini, Stephania; Claridge, Hugh; Corkery, John; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2014-03)Introduction: methoxetamine (MXE; ‘special M’) is a novel psychoactive substance that first appeared in 2010 as a legal alternative to ketamine and, despite now being a Class B drug, is still widely marketed via the internet ... -
UK deaths associated with ‘Z’ drugs (Zopiclone, Zolpidem & Zaleplon)
Casula, Salvatore; Claridge, Hugh; Corkery, John; Gimeno Clemente, Carla; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (Advisory Council on the Misuse of Drugs, 2013-09-05) -
The Unregulated Psychoactive Compound: ‘Benzo Fury’
Gimeno Clemente, Carla; Chiappini, Stephania; Claridge, Hugh; Corkery, John; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2013-12)Introduction: The ‘legal high’ ‘Benzo Fury’ [1-(benzofuran-5-yl)propan-2-amine (5-APB) and 1-(benzofuran-6-yl)propan-2-amine (6-APB)] is an unregulated psychoactive compound which has similar effects as known controlled ...