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Browsing by Author "Martinho, Nuno"
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Molecular modeling to study dendrimers for biomedical applications
Martinho, Nuno; Florindo, Helena; Silva, Liana; Brocchini, Steve; Zloh, Mire; Barata, Teresa (2014-12-08)Molecular modeling techniques provide a powerful tool to study the properties of molecules and their interactions at the molecular level. The use of computational techniques to predict interaction patterns and molecular ... -
Poly-glutamic dendrimer-based conjugates for cancer vaccination - a computational design for targeted delivery of antigens
Moura, Liane; Martinho, Nuno; Silva, Liana; Barata, Teresa S; Brocchini, Steve; Florindo, Helena; Zloh, Mire (2017-08-10)Computational techniques are useful to predict interaction models and molecular properties for the design of drug delivery systems, such as dendrimers. Dendrimers are hyperbranched macromolecules with repetitive building ... -
Practical computational toolkits for dendrimers and dendrons structure design
Martinho, Nuno; Silva, Liana; Florindo, Helena; Brocchini, Steve; Barata, Teresa S; Zloh, Mire (2017-09-30)Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties ... -
Rational design of novel fluorescent tagged glutamic acid dendrimers with different terminal groups and in-silico analysis of their properties
Martinho, Nuno; Silva, Liana; Florindo, Helena; Brocchini, Steve; Zloh, Mire; Barata, Teresa S (2017-09-25)Dendrimers are hyperbranched polymers with a multifunctional architecture that can be tailored for the use in various biomedical applications. Peptide dendrimers are particularly relevant for drug delivery applications due ...